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本文采用血清性激素水平测定、精液检查、第二性征体格检查,对已停用雷公藤多式片(TⅡ)平均9.5年的小儿肾病,进行了追踪观察,并以停用强的松平均7.2年同类病人作对照,提示Ⅱ对女性患儿青春发育期无明显影响,对部分男性患儿生精过程可能有一定影响。
In this study, serum sex hormone levels, semen examinations, and physical examinations of secondary sexual characteristics were used to track the observation of pediatric nephropathy with an average of 9.5 years of triptolide tolerance (TII) and to disable prednisone. An average of 7.2 years of similar patients as a control, suggesting that no significant impact on the development of female children with puberty, some children may have a certain influence on the spermatogenesis process.