体外循环作为辅助手段广泛地应用于心脏血管手术。最近,患者高龄化的同时,术前多伴有脑神经合并症。所以,在体外循环中保护脑血流或脑机能的有效指标是必要的。现在,作为体外循环中脑缺血的指标,如下述有各种各样的方法。但把复杂的中枢神经系统机能用单一的指标进行确切的评价也决非易事。体外循环中,脑缺血的指标最广泛应用的就是灌 Cardiopulmonary bypass as an adjunct to cardiovascular surgery widely used. Recently, patients with aging, more preoperative complications associated with cranial nerves. Therefore, in the cardiopulmonary bypass in the protection of cerebral blood flow or brain function of the effective indicators are necessary. Now, as a marker of cerebral ischemia during cardiopulmonary bypass, there are a variety of methods as described below. However, it is no easy task to evaluate the complex central nervous system function with a single indicator. Cardiopulmonary bypass, the most widely used indicator of cerebral ischemia is irrigation