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Preparation and evaluation of a new releasable PEGylated tumor necrosis factor-α （TNF-α） conjugate f
[期刊论文] 作者：DAI ChuanYun,FU Ya,CHEN ShaoCh,
来源：中国科学：生命科学英文版 年份：2013
To design a releasable PEGylated TNF-α(rPEG-TNF-α ), a cathepsin B-sensitive dipeptide (Val-Cit moiety) was inserted into conventional PEG-modified TNF- (PEG-...
Linkage with cathepsin B-sensitive dipeptide promotes the in vitro and in vivo anticancer activity o
[期刊论文] 作者：DAI ChuanYun,FU Ya,LI Biao,WAN,
来源：中国科学：生命科学英文版 年份：2011
To improve the pharmacological profile of tumor necrosis factor alpha(TNF-α),we have synthesized a new PEGylated prodrug,PEG-vcTNF-α,using a cathepsin B-sensi...
Preparation and evaluation of a new releasable PEGylated tumor necrosis factor-α(TNF-α) conjugate fo
[期刊论文] 作者：DAI ChuanYun,FU Ya,CHEN ShaoCheng,LI Biao,YAO Bo,LIU WanHong,ZHU LiQing,CHEN Nan,CHEN Ji,ZHANG Qiang,,
来源：Science China(Life Sciences) 年份：2013
To design a releasable PEGylated TNF-α(rPEG-TNF-α ), a cathepsin B-sensitive dipeptide (Val-Cit moiety) was inserted into conventional PEG-modified TNF- (PEG-...
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