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[会议论文] 作者:Zhuguo Liu,Longxiao Zhang,Qiuyun Dai,
来源:10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份:2014
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Identification and Expression of a Novel conotoxin with ten pairs of disulfide bonds from Conus dist
[会议论文] 作者:Zhuguo Liu,Kejun Zhang,Chuanxia Wu,Qiuyun Dai,
来源:10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份:2014
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Identification and Expression of a Novel conotoxin with ten pairs of disulfide bonds from Conus dist
[会议论文] 作者:Zhuguo Liu,Kejun Zhang,Chuanxia Wu,Qiuyun Dai,
来源:10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份:2014
Cone snails are a large genus of venomous snails that use a complex mixture of physiologically active peptides for prey capture.These active peptides secreted from venom duct of Cone snails named as c...
[期刊论文] 作者:Zhuguo Liu,Zheng Yu,Na Liu,Chongjia Zhao,Jie Hu,Qiuyun Dai,
来源:生物化学与生物物理学报(英文版) 年份:2010
In our efforts for cloning novel I2-superfamily conotoxins using the signal peptide sequence,we identified a novel eonotoxin Lt12.4 from Conus iitteratus.This g...
[会议论文] 作者:Jianwei Cheng,Yuxian He,Mingxin Dong,Hong Lu,Shuangshuang Hou,Jingling Li,Shibo Jiang,Qiuyun Dai,
来源:2006中国天津世界艾滋病日科技会议 年份:2006
Background:Enfuvirtide (T20),a fusion inhibitor derived from the C-terminal heptad repeat region (CHR) of HIV-1 gp41 is the only peptidic anti-HIV drug licensed by the US FDA.However,concerns have bee...
A novel ω-conotoxin Bu8 inhibiting N-type voltage-gated calcium channels displays potent analgesic a
[期刊论文] 作者:Jinqin Chen,Xinhong Liu,Shuo Yu,Jia Liu,Rongfang Chen,Yunxiao Zhang,Ling Jiang,Qiuyun Dai,
来源:药学学报(英文版) 年份:2021
ω-Conotoxins inhibit N-type voltage-gated calcium(Cav2.2)channels and exhibit efficacy in attenuating neuropathic pain but have a low therapeutic index.Here,we synthesized and characterized a novel ω-conotoxin,Bu8 from Conus bullatus,whic......
Diaminodiacid bridge improves enzymatic and in vivo inhibitory activity of peptide CPI-1 against bot
[期刊论文] 作者:Jintao Shen,Jia Liu,Shuo Yu,Yunzhou Yu,Chao Huang,Xianghua Xiong,Junjie Yue,Qiuyun Dai,
来源:中国化学快报(英文版) 年份:2021
The replacement of the disulfide bridge of CPI-1, a peptide inhibitor of light chain of Botulinum toxin serotype A, with the thioether-containing and biscarba-containing diaminodiacid bridge leads to a significant decrease in the degradatio......
[会议论文] 作者:Qiuyun Dai,Jianwei Cheng,Mingxin Dong,Jie Hu,Shibo Jiang,Yuxian He,Hong Lu,Jingjing Li,Zhi Qi,Weiguo,
来源:第十届中国国际多肽学术大会(10th Chinese International Peptide Symposium)( 年份:2008
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[会议论文] 作者:Qiuyun Dai,Shibo Jiang,Yuxian He,Jianwei Cheng,Hong Lu,Jingjing Li,Mingxin Dong,Jie Hu,Zhi Qi,Weiguo,
来源:第十届中国国际多肽学术大会(10th Chinese International Peptide Symposium)( 年份:2008
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A novel stearic acid-modified hirudinpeptidomimetic with improved pharmacokinetic properties and ant
[会议论文] 作者:Yan Zhang,Guozhu Han,Xian Li,Mingxin Dong,Shuo Yu,Yu Wang,Jie Hu,Huiqin Guo,Yuanguo Cheng,Li Lv,Qiuyun Dai,
来源:第12届生物毒素研究及医药应用学术大会 年份:2015
A novel hirudin isoform 3 mimetic peptide, named peptide S2, has been prepared by introduction of a stearic acid modification.Peptide S2 exhibited superior inhibitory activity to hirulog-1 (Bivariludi...
[会议论文] 作者:Qiuyun Dai,Zhuguo Liu,Yan Xu,Qin Dai,Cui Zhu,Shuo Yu,Ting Sun,Shuo Wang,Rong Ding,Mingxue Yu,Mingxin,
来源:第十三届中国国际多肽大会 年份:2014
Alpha-conopeptides belongs to a superfamily of conotoxins and specifically targets nAChR.Some peptides that inhibit nAChR alpha9alpha10,alpha3beta2 exhibits...
[会议论文] 作者:Qiuyun Dai,Zhuguo Liu,Yan Xu,Qin Dai,Cui Zhu,Shuo Yu,Ting Sun,Shuo Wang,Rong Ding,Mingxue Yu,Mingxin,
来源:第十三届中国国际多肽大会 年份:2014
Alpha-conopeptides belongs to a superfamily of conotoxins and specifically targets nAChR.Some peptides that inhibit nAChR alpha9alpha10,alpha3beta2 exhibits...
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