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[会议论文] 作者：Xingxu Huang,
来源：第三届上海科技大学免疫化学国际生物论坛 年份：2016
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[期刊论文] 作者：Yao LIU,Xingxu HUANG,Xiaolong WANG,
来源：农业科学与工程前沿（英文版） 年份：2020
Genome editing based on CRISPR/Cas9 system enables unprecedented breakthroughs in genomic research and the engineering of variants associated to clinical diseas...
Mitotic chromosome mis-segregation mediated by Separase phosphosite mutation leads to aneuploidy and
[会议论文] 作者：Xingxu Huang,Meizhi Wang,Jingmei Chen,
来源：第十一次中国生物物理学术大会 年份：2009
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[会议论文] 作者：Xingxu Huang,Weizhi Ji,Jiahao Sha,
来源：第三届全国发育生物学大会 年份：2016
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Mitotic chromosome mis-segregation mediated by Separase phosphosite mutation leads to aneuploidy and
[会议论文] 作者：Xingxu Huang,Meizhi Wang,Jingmei Chen,
来源：第十一次中国生物物理学术大会 年份：2009
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[期刊论文] 作者：Shaoshuai Mao,Yajing Liu,Shisheng Huang,Xingxu Huang,Tian Chi,
来源：遗传学报 年份：2019
Site-directed RNA editing (SDRE) is invaluable to basic research and clinical applications and has emerged as a new frontier in genome editing.The past few year...
[会议论文] 作者：Yu Kang,Bo Zheng,Bin Shen,Yongchang Chen,Jiahao Sha,Weizhi Ji,Xingxu Huang,
来源：第三届全国发育生物学大会 年份：2016
Mutations in the DAX1 locus cause X-linked adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH),which manifest with primary adrenal insufficiency and incomplete or absent sexual m...
[会议论文] 作者：Yuanwu Ma,Wei Chen,Xu Zhang,Lei Yu,Wei Dong,Shuo Pan,Shan Gao,Xingxu Huang,Lianfeng Zhang,
来源：第十二届中国实验动物科学年会 年份：2016
Precise modifications such as site mutation,codon replacement,insertion or precise targeted deletion are needed for studies of accurate gene function.The CRISPR/Cas9 system has been proved as a powerf...
[会议论文] 作者：Jiajie Hou,Yongxiang Xia,Runqiu Jiang,Dianyu Chen,Juan Xu,Lei Deng,Xingxu Huang,Xuehao Wang,Beicheng,
来源：2013中国器官移植大会 年份：2013
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[会议论文] 作者：Yuanwu Ma,Lianfeng Zhang,Jing Ma,Xu Zhang,Wei Chen,Lei Yu,Yingdong Lu,Lin Bai,Bin Shen,Xingxu Huang,
来源：2014第十一届中国实验动物科学年会 年份：2014
The type Ⅱ bacterial CRISPR/Cas system is a very valuable genome-engineering tool, which has been widely used in genome editing of variety of organisms.Previously, we generated the floxed alleles in r...
[期刊论文] 作者：Yao Liu,Guang Yang,Shuhong Huang,Xiangyang Li,Xin Wang,Guanglei Li,Tian Chi,Yulin Chen,Xingxu Huang,Xiaolong,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnThe most advanced prime editor 3 (PE3) system comprises the editor,a fusion protein of Cas9 H840A nickase and mutant reverse transcriptase (RTase) (hereafter termed NMRT),a prime editing guide RNA (pegRNA) and an alternative s......
[期刊论文] 作者：Li,Yajing Liu,Yanting Zeng,Jianan Li,Lijie Wang,Guang Yang,Dunjin Chen,Xiaoyun Shang,Jia Chen,Xingxu Huang,
来源：蛋白质与细胞 年份：2017
Dear Editor,CRISPR/Cas9 is a powerful tool for genome editing (Komor et al.,2017).Recently,it has been employed in several attempts to edit the human embryos (L...
Efficient Generation of Gene-Modified Pigs HarboringPrecise Orthologous Human Mutation via CRISPRCas
[会议论文] 作者：Xiaoyang Zhou,Lulu Wang,Yinan Du,Fei Xie,Liang Li,Yu Liu,Chuanhong Liu,Shiqiang Wang,Shibing Zhang,Xingxu Huang,
来源：第十二届中国实验动物科学年会 年份：2016
Precise genetic mutation of model animals is highly valuable for functional investigation of human mutations.Clustered regularly interspaced short palindrom...
Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPRCa
[会议论文] 作者：Xiaoyang Zhou,Lulu Wang,Yinan Du,Fei Xie,Liang Li,Yu Liu,Chuanhong Liu,Shiqiang Wang,Shibing Zhang,Xingxu Huang,
来源：第十二届中国实验动物科学年会 年份：2016
Precise generic mutation of model animals is highly valuable for functional investigation of human mutations.Clustered regularly interspaced short palin-dro...
GGPP-mediated protein geranylgeranylation in oocyte is essential for the establishment of oocyte-gra
[会议论文] 作者：Diao,Yong-Juan Sang,Rui-Lou Zhu,Na Xu,Xiu-Xing Wang,Zhong Chen,Wei-Wei Tao,Bing Yao,Hai-Xiang Sun,Xingxu Huang,
来源：第三届全国发育生物学大会 年份：2016
The primary-secondary follicle transition,which is essential to provide ova for later reproductive life,requires the bidirectional communication between the...
[期刊论文] 作者：尹亚飞,颜丕熙,Jinlong Lu,Guang Song,Yangyang Zhu,Zhaohui Li,Bin Shen,Xingxu Huang,Heng Zhu,Stuart H.Orkin,沈晓骅,
来源：科学新闻 年份：2016
文章简介长链非编码RNA(lncRNA)是一类长度大于200nt且不编码蛋白质的RNA转录物。近年来,随着高通量测序的普及越来越多的lncRNA被鉴定出来,据估算人和小鼠的基因组中lncRNA...
[会议论文] 作者：Xiaoyang Zhou,Jian Li,Yu Liu,Jianying Wang,Jiankui Zhou,Bian Hu,Nannan Kang,Jimin Gao,Liqing Yu,Xingxu Huang,
来源：2016华南实验动物科学国际研讨会、第三届实验小型猪国际论坛暨广东·九州实验动物学术交流会 年份：2016
Co-injection of zygotes with Cas9 mRNA and sgRNA has been proven to be an efficient gene-editing strategy for genome modification of different species.Genetic engineering in pigs holds a great promise...
Production of Human Albumin in Pigs Through CRISPR/Cas9-Mediated Knockin of Human cDNA into Swine Al
[会议论文] 作者：Junyi Jiang,Xiaoyang Zhou,Lei Song,Lulu Wang,Chen Ding,Jun Qin,Liping Liu,Weihua Wang,Jianqiao Liu,Xingxu Huang,
来源：2016华南实验动物科学国际研讨会、第三届实验小型猪国际论坛暨广东·九州实验动物学术交流会 年份：2016
Precise genome modifcation in large domesticated animals is desirable under many circumstances.In the past it is only possible through lengthy and burdensome cloning procedures.Here we attempted to ac...
SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facili
[期刊论文] 作者：Ma,Boxing Jin,Yulin Zhou,Su He,Jinhua Huang,Xun Xu,Yan Zou,Ping Li,Aibin Liang,Jia Liu,Tian Chi,Xingxu Huang,
来源：科学通报（英文版） 年份：2021
A key to tackling the coronavirus disease 2019 (COVID-19) pandemic is to understand how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) manages to outsmart host antiviral defense mecha-nisms.Stress granules (SGs),which are asse......
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