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Ultrasensitive nanoLC-MS proteomic analysis using ultranarrow-bore separation column with integrated
[会议论文] 作者：Yu Liang,Xudong Zhu,Ci Wu,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：2016年分析化学前沿国际研讨会及中美分析化学研讨会 年份：2016
Nano-scale liquid chromatography-mass spectrometry(nanoLC-MS)has been a routine tool in proteomic research,however,the analysis of trace sample(e.g.,cells f...
[会议论文] 作者：Kaiguang Yang,Senwu Li,Jianxi Liu,Lukuan Liu,Lihua Zhang,Yukui Zhang,
来源：2016年分析化学前沿国际研讨会及中美分析化学研讨会 年份：2016
To achieve the simultaneous capture of various target proteins,the multi-epitope templates imprinted particles were developed by phase inversion-based polye...
[会议论文] 作者：Deng Qiliang,Liu Jinxiang,Zhang Lihua,Liang Zhen,Zhang Weibing,Zhang Yukui,
来源：第五届中国蛋白质组学大会暨首届粤港蛋白质组学学术交流会 年份：2007
...
[会议论文] 作者：Yuan Zhou,Zhigang Sui,Jiahui Liu,Chao Yang,Lihua Zhang,Yukui Zhang,
来源：中国化学会第二届全国质谱分析学术报告会 年份：2015
Pseudo-isobaric labeling,based on the differences of mass defect values of atoms and their isotopes,shows great potential in accurate proteome quantification1.I...
[会议论文] 作者：Shuaibin Wu,Lei Zhang,Kaiguang Yang,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 年份：2011
The "Shot-gun" method is one of the most popular tools in current proteomics study.In this method, digestion is the key process for protein profile via mass spectrometry (MS) analysis.Traditionally, d...
[会议论文] 作者：Liang Gao,Tingting Wang,Jie Zhang,Lihua Zhang,Weibing Zhang,Yukui Zhang,
来源：DaLian Internationall Symposia and Exhibition on Chromatogra 年份：2007
For supercritical fluid chromatography (SFC), the mobile phase is generally of high diffusivity and low viscosity, which is achievable with the combination of a compressible fluid, usually carbon diox...
[会议论文] 作者：Tingting Wang,Junfeng Ma,Guijie Zhu,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：The 24th International Symposium on Microscale Bioseparation 年份：2009
...
Fragment Ion Pairs Based Proteomics Search Algorithm for improving the Quantification Coverage of Is
[会议论文] 作者：Yichu Shan,Shen Zhang,Qi Wu,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：第八届中国蛋白质组学大会 年份：2013
Quantitative proteomics plays an important role in the comparison of biological systems.The incorporation of stable isotopes to achieve differentially labeled peptides allowing for a comparison of rel...
[会议论文] 作者：Hui Wang,Jicheng Duan,Yongzheng Cong,Lihua Zhang,Weibing Zhang,Yukui Zhang,
来源：DaLian Internationall Symposia and Exhibition on Chromatogra 年份：2007
Micro total analytical system (μ-TAS) has been developed rapidly in resent years.Although microchip zone electrophoresis could offer high separation efficiency, the resolution should still be improved...
[会议论文] 作者：Liangliang Sun,Guijie Zhu,Zhen Liang,Weibing Zhang,Lihua Zhang,Yukui Zhang,
来源：The 24th International Symposium on Microscale Bioseparation 年份：2009
...
[会议论文] 作者：Yu Liang,Oun Zhao,Ci Wu,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 年份：2011
Packed capillary columns are widely used in micro/nano-scale high-performance liquid chromatography, with advantages of high sample capacity, high separation efficiency and good reproducibility.Howeve...
[会议论文] 作者：Yuanbo Chen,Bo Jiang,Nan Deng,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：43rd International Symposium on High Performance Liquid Phas 年份：2015
In eukaryotic cells,chromosomal DNA is packed in highly organized chromatin structures,with the assist of four core histones(H2A,H2B,H3,and H4)[1].Post-translational modification(PTM) in histones cont...
[会议论文] 作者：Kaiguang Yang,Jianxi Liu,Senwu Li,Qinran Li,Qi Wu,Lihua Zhang,Yukui Zhang,
来源：第八届分子印迹国际会议MIP2014 年份：2014
The plasma proteome can be considered the most important analyte for monitoring the physical condition of a patient,because blood flows throughout the body...
[期刊论文] 作者：Shuaibin Wu,Hongfei Zhang,Kaiguang Yang,Junfeng Ma,Zhen Liang,Lihua Zhang,Yukui Zhang,,
来源：Science China Chemistry 年份：2015
Fast and efficient sample preparation methods are a prerequisite for protein identification in bottom-up proteomics. Here, an innovative microwave irradiation s...
[会议论文] 作者：Zhigang Sui,Yejing Weng,Qun Zhao,Fei Fang,Xudong Zhu,Lihua Zhang,Yukui Zhang,
来源：第十六届北京分析测试学术报告会 年份：2015
Velvet antlers are the unique organs that display an annual cycle of full regeneration in mammals [1]....
[期刊论文] 作者：Huiming Yuan,Zhongpeng Dai,Xiaodan Zhang,Baofeng Zhao,Hongwei Chu,Lihua Zhang,Yukui Zhang,
来源：中国科学：化学（英文版） 年份：2021
The bottom-up strategy for proteome analysis typically employs a multistep sample preparation workflow that suffers from being time-consuming and sample loss or...
[会议论文] 作者：Yu Liang,Yi Min,Wenya Shao,Jianxi Liu,Zheng liang,Lihua Zhang,Yukui Zhang,
来源：43rd International Symposium on High Performance Liquid Phas 年份：2015
...
Boronic Acid Functionalized Core-shell Polymer Nanoparticles for Selective Enrichment of Glycopeptid
[会议论文] 作者：Jianxi Liu,Yanvan Qu,Kaiguang Yang,Qi Wu,Lihua Zhang,Yukui Zhang,Zheng liang,
来源：第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 年份：2011
Glycosylation is one of the most common post-translational modification of proteins, and plays a major role in a variety of biological activities, e.g.receptor-ligand interaction, signal transduction...
An efficient proteomic strategy for membrane proteome analysis combining protein prefractionation by
[会议论文] 作者：Oun Zhao,Liangliang Sun,Huiming Yuan,Qi Wu,Zhen Liang,Lihua Zhang,Yukui Zhang,
来源：第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 年份：2011
Integral membrane proteins (IMPs) play a critical role in regulating a host of cellular processes, including intercellular communication, vesicle trafficking, ion transport, protein translocation/inte...
[会议论文] 作者：Hao Jiang,Huiming Yuan,Simin Xia,Qun Zhao,Qi Wu,Lihua Zhang,Yukui Zhang,
来源：第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 年份：2011
For "bottom-up" proteomic analysis, protein digestion prior to MS analysis is indispensable1,2 However, traditional in-solution digestion often suffers from time-consuming, sample loss and contaminati...
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