6-mercaptopurine相关论文
目的:系统评价儿童急性淋巴细胞白血病(acute lymphoblastic leukemia，ALL)患儿中NUDT15基因c.415>C位点多态性与化疗中6-巯基嘌呤(......
目的:探讨儿童急性淋巴细胞白血病(acute lymphoblastic leukemia，ALL)中n NUDT15基因单核苷酸多态性(single nucleotide poly......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
巯嘌呤用于治疗儿童急性淋巴细胞白血病，药物相关的骨髓抑制和肝毒性可威胁患儿生命，由此导致的化疗中断或停止增加疾病复发风险。可......
The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance
Pediatric acute lymphoblastic leukemia(ALL) affects a substantial number of children every year and requires a long and ......
Theoretical Investigation of Structures, Bonding and Electronic Properties for the Complexes of 6-Me
本文通过对荣华二采区10...
Determination of 6-Mercaptopurine in Rat Blood by Microdialysis Coupled with High Performance Liquid
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
巯嘌呤甲基转移酶是硫唑嘌呤代谢过程中的重要代谢酶,巯嘌呤甲基转移酶遗传多态性与硫唑嘌呤的药物不良反应密切相关.充分认识巯嘌......
目的 调查急性淋巴细胞性白血病(acute lymphoblastie leukemia,ALL)患儿,维持化疗期间巯嘌呤(6-mercaptopurine,6-MP)的耐受性,为......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
目的 分析严重不耐受巯嘌呤(6-MP)的ALL患儿的临床特征,并根据随访结果进一步了解这些患儿停化疗后不良反应的恢复情况.方法 选取2......
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel dis
AIM:To investigate the efficacy of 6-mercaptopurine(6-MP) in cases of azathioprine (AZA) hypersensitivity in patients wi......
Determination of 6-Mercaptopurine in Rat Blood by Microdialysis Coupled with High Performance Liquid
A new chemically modified electrode(CME) immobilized on the surface of multi-wall carbon nanotubes functionalized with c......
试验发现6-巯基嘌呤对Luminol-H2O2-OH-体系的化学发光有较强的增敏作用。据此建立了一种流动注射化学发光增强法测定6-巯基嘌呤的......
目的 通过对硫唑嘌呤中间代谢物6-巯基嘌呤（6-mercaptopurine，6-MP）药动学的研究，初步探讨巯嘌呤甲基转移酶（thiopurine methyltransfer......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel dis
瞄准: 在 azathioprine (AZA ) 的情况下调查 6-mercaptopurine (6-MP ) 的功效在有煽动性的肠疾病的病人的超敏性。方法：29 以前证......
在p H 5.5的B-R缓冲溶液中,6-巯基嘌呤与纳米金反应后,纳米金粒子溶液的颜色由酒红色逐渐变为蓝色,其最大吸收波长从525 nm移至670......
利用循环伏安法制备了银掺杂聚L-甲硫氨酸修饰玻碳电极（Ag—PLM／GCE），研究了6-巯基嘌呤在该修饰电极上的电化学行为，建立了循环伏安法测......
应用循环伏安法和微分脉冲伏安法研究了6-糠氨基嘌呤（6-KT）和6-巯基嘌呤（6-MP）在汞电极上的电化学行为及与小牛胸腺DNA的相互作用．结果......
6-巯基嘌呤(6-MP)是急性淋巴细胞白血病(ALL)维持治疗阶段的重要药物,其副作用包括肝毒性和骨髓抑制,不同个体对6-MP的耐受差异较......
本文报道了用紫外分光光度法测定6-巯基嘌呤核苷注射剂含量的方法，该法快速简便准确，浓度与吸收度的相关第数r=0.9999，当加样量分别为......
Inclusion-Interaction Assembly Strategy for Constructing pH/Redox Responsive Micelles for Controlled
An inclusion-interaction assembly strategy was used to construct novel pH/redox responsive core-shell micelles with hydr......
Efficacy of low-dose thiopurine therapy for the induction of remission in steroid-dependent ulcerati
Background: The role of azathioprine (AZA) and 6-mercaptopurine (6-MP) in the induction of remission in patients with ul......
目的：建立一种快速、灵敏、高效的方法，检测儿童急性淋巴细胞白血病红细胞中硫鸟嘌呤核苷酸浓度。方法：应用反相高效液相色谱（RT-HPLC）......
首次对6-巯基嘌呤(6MP)和2-巯基嘌呤(2MP)在银电极上的伏安行为进行了比较研究,并同时对它们的衍生物的电化学性质进行了探讨.结果......
在0.025mol/L Na_2HPO_4-NaH_2PO_4(pH6.7)介质中,6—巯基嘌呤与镉离子的配合物可在-0.82V(vs SCE)产生灵敏的阴极化波。其二阶导......
本文报道用高效液相色谱法测定人血浆中硫唑嘌呤和巯嘌呤浓度的方法。样品用三氯醋酸沉淀蛋白后，取上清液直接进样。以ＳｐｈｅｒｉｓｏｕｂＣ１８为固定相，甲醇......
ＣｈｅｍｉｌｕｍｉｎｅｓｃｅｎｃｅＤｅｔｅｒｍｉｎａｔｉｏｎｏｆ６－ＭｅｒｃａｐｔｏｐｕｒｉｎｅｉｎＰｈａｒｍａｃｅｕｔｉｃａｌｓＨＥＺｈｉ－ｋｅ，ＬＩＵＸｉｎｇ－ｌｉａｎ，ＬＵＯＱｉｎｇ－ｙａｏ，ＹＵＸｉ－ｍａｏａｎｄＺＥＮＧＹｕｎ＇ｅ（Ｄｅｐａｒ.........
Arbitrarily, modern day treatment of inflammatory bowel disease begins with the introduction of immuno- suppressives for......
草鱼卵巢细胞ＧＣＧ经乙基甲磺酸诱变，稳定表达３代以后，采取逐步提高培养基中６－巯基嘌呤的方法，获得对６－ＭＰ稳定抗生的细胞，暂定名ＦＭＲ－１。本文比较了ＧＣＧ细胞及......
目的：探讨了重原子盐Cd(Ac)2和Zn(Ac)2对6－巯基嘌呤室温磷光（RTP）的影响。方法：配制一定浓度的6－巯基嘌呤溶液，选择不同的固体基质及酸度......
