azathioprine相关论文
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Preliminary study on azathioprine plus corticosteroids treatment in Chinese patients with neuromyeli
Objective: To investigate the efficacy and safety of azathioprine (AZA) plus low dose corticosteroids in Chinese patient......
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Bone marrow inhibition induced by azathioprine in a patient without mutation in the thiopurine S-met
BACKGROUND Azathioprine(AZA)and its close analog 6-mercaptopurine are thiopurines widely used in the treatment of patien......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
目的评价硫唑嘌呤/巯嘌呤对男性炎性肠病患者生育的影响。方法检索Pub Med、Cochrane Library、中国生物医学文献数据库、中国期刊......
1例29岁女性患者因克罗恩病口服泼尼松治疗，初始剂量40 mg/d，3个月后减量至25 mg/d，因病情出现反复，泼尼松恢复初始剂量并加服硫唑嘌呤......
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目的 探讨肾移植受者红细胞中硫嘌呤甲基转移酶(TPMT)活性与硫唑嘌呤导致的血液毒性和肝脏毒件等不良反应的关系.方法 应用高效液......
目的:对比二者在视神经脊髓炎谱系疾病(NMOSD)患者中应用的安全性及有效性.方法:回顾性收集34例服用硫唑嘌呤(AZA)或环孢素A(Cy-A)......
目的：探讨硫唑嘌呤联合小剂量曲安西龙治疗老年慢性免疫性血小板减少症（CITP）的疗效，并观察其不良反应。方法56例非重症的老年CITP患者......
Preventive role of chamomile flowers and fennel seeds extracts against liver injury and oxidative st
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
巯嘌呤甲基转移酶是硫唑嘌呤代谢过程中的重要代谢酶,巯嘌呤甲基转移酶遗传多态性与硫唑嘌呤的药物不良反应密切相关.充分认识巯嘌......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
AIM: To evaluate the role of azathioprine (AZA) in Indian patients with ulcerative colitis over longer duration of time.......
The early hypersensitivity reaction and late bone marrow depression are well-known side-effects of azathioprine, whereas......
Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hep
AIM: To determine the efficacy of tacrolimus on clinical status, histopathological status and biochemical markers in pat......
Azathioprine is Currently the key drug in the maintenance treatment of inflammatory bowel diseases. However, there are s......
Although systemic steroids are highly efficacious in ulcerative colitis (UC),failure to respond to steroids sUll poses a......
BACKGROUND Autoimmune hepatitis can cause liver fibrosis,liver cirrhosis,and hepatocellular carcinoma.Its treatment opti......
目的探究英夫利昔单抗联合硫唑嘌呤在克罗恩病患者中的应用效果。方法选取2017年2月至2018年2月医院收治的68例克罗恩病患者,采用......
目的:回顾性分析他克莫司在重症肌无力(MG)患者中的应用,并与硫唑嘌呤进行对比研究。方法:选择我科于2008年4月至2016年7月收治的......
Pharmacogenetics of azathioprine in inflammatory bowel disease: A role for glutathione-S-transferase
Azathioprine is a purine antimetabolite drug commonly used to treat inflammatory bowel disease(IBD).In vivo it is active......
BACKGROUND Autoimmune hepatitis (AIH) is a rare chronic inflammatory liver disease with a high risk of progression to li......
目的分析本院门诊患者硫唑嘌呤片的使用和超说明书用药情况,为临床合理用药提供参考。方法抽取本院2013-01~06含有硫唑嘌呤片的门......
目的 比较以硫唑嘌呤（AZA）或吗替麦考酚酯（MMF）为基础的两种免疫抑制方案，对肾移植术后感染的影响，并探讨肺部感染与尿路感染的病原学分......
目的:探讨强的松、硫唑嘌呤联合乙酰半胱氨酸治疗间质性肺炎的效果。方法:回顾性收集郑州市第六人民医院2019年3月-2020年3月接收......
目的：本研究旨在探索次黄嘌呤鸟嘌呤磷酸核糖转移酶（HGPRT）活性及基因多态性与硫唑嘌呤（AZA）所致不良反应的相关性,为临床合理使用AZA提......
目的在SDUC患者中,评估AZA作为无激素缓解维持治疗药物的疗效和安全性。方法纳入该院自2012年1月—2017年6月SDUC患者,在该开放性......
Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hep
瞄准：与类固醇在病人在临床的地位，组织病理学说的地位和生物化学的标记上决定 tacrolimus 的功效倔强的自体免疫的肝炎(AIH ) 。方......
目的:比较肾移植受者应用霉酚酸酯(MMF)与硫唑嘌呤(Aza)的临床疗效.方法:肾移植术后患者86例随机分为MMF组,即用环孢素(CsA)加MMF......
目的初步探讨肾移植后吗替麦考酚酯(MMF)替换硫唑嘌呤(Aza)的安全性及其临床效果.方法回顾分析16例由Aza转换为MMF的患者的临床资......
目的 研究汉防己甲素（Tet)对硫唑嘌呤（Aza)致大鼠肝损伤的保护作用。方法 大鼠分为三组：①对照组；②Aza组；③Aza+Tet组。给药量分别为......
目的：比较霉酚酸酯（MMF）、硫唑嘌呤（Aza）在肾移植病人中的临床效果。方法：肾移植术后服用霉酚酸酯、硫唑嘌呤患者各28例，均采用同服环孢菌......
目的:研究硫唑嘌呤(azathioprine,AZP)对环孢素A(cyclosporine CSA)血药浓度及药动学的影响.方法:8只家兔灌胃法给CSA口服液(15 mg......
用荧光光谱法和紫外-可见光谱法研究了在模拟人体生理条件下，硫唑嘌呤和牛血清白蛋白（BSA）结合反应的特征，发现硫唑嘌呤对BSA有较强的......
目的客观评价肾移植术后骁悉(mycohpenolate mofetil,MMF)与硫唑嘌呤(azathioprine,AZA)抗排斥反应效果的差别.方法计算机检索Medl......
目的 系统评价肾移植术后免疫抑制剂骁悉(mycophenolate mofetil,MMF)与硫唑嘌呤(azathioprine,AZA)导致的不良反应发生情况.方法 ......
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercap
AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) ......
早超敏性反应和迟了的骨髓消沉是 azathioprine 的著名副作用，而间质性肺炎是稀罕复杂并发症。一个 40 年的老男病人由于广泛的 ulc......
Azathioprine 当前是在煽动性的肠疾病的维护治疗的关键药。然而，仍然有要决定的一些实际问题：一个人是我们多长必须维持这药。给疾......
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel dis
瞄准: 在 azathioprine (AZA ) 的情况下调查 6-mercaptopurine (6-MP ) 的功效在有煽动性的肠疾病的病人的超敏性。方法：29 以前证......
Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological thera
在关键可修改的风险因素以后的十年被识别的、心血管的疾病尚待有高胆固醇层次的 1/4 个人达到了的可防止的死亡，和仅仅死亡的领先......
Clinical effects of adalimumab treatment with concomitant azathioprine in Japanese Crohn’s disease p
AIM:To assess adalimumab’s efficacy with concomitant azathioprine (AZA) for induction and maintenance of clinical remis......
AIM:To suggest infliximab(IFX) is effective for acute severe ulcerative colitis,from real-life clinical practice.METHODS......
Although a great variety of new drugs have been introduced for the therapy of inflammatory bowel diseases so far,a defin......
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis
AIM: To investigate if azathioprine could reduce adenoma formation in ApcMin/+, a mouse model of sporadic intestinal tum......
