CO-DELIVERY相关论文
Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-
Co-delivery of chemotherapeutics and immunostimulant or chemoimmunotherapy is an emerging strategy in cancer therapy.The......
Preparation and anti-tumor application of hyaluronic acid-based material for disulfide and copper io
Disulfide (DSF) has been proved good anti-tumor effect and even better with coadministration of Cu2+.In this work,we rep......
Co-Delivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multi
Despite progress, combination therapy of various functional drugs to enhance the efficiency against multidrug resistance......
Co-delivery of siRNA and docetaxel into tumor by polypeptide micelles based on PEG-PLL-PLLeu tribloc
Combination of two or more therapeutic strategies with different mechanisms can cooperatively impede cancer development.......
Fabrication of multi-compartmental microparticles with tailored spatial configuration for co-deliver
In drug delivery,the use of multi-compartmental microparticles for encapsulation and delivery of multiple drugs has rece......
Truncated bFGF Peptide-medicated Active Targeting System Simultaneously Loaded with PEDF and Paclita
The ligand-mediated active targeting system is one of ideal gene delivery systems.Fibroblast growth factor receptors(FGF......
Co-delivery of all-trans-retinoic acid and doxorubicin for cancer therapy with synergistic inhibitio
Cancer stem cells (CSCs),are known to be resistant to chemotherapy and radiotherapy and are associated with tumor metast......
Nanoparticle-assisted combination therapy against triple negative breast cancer by using miR-34a and
Metastatic relapse,development of drug resistance in cancer cells and adverse side effects of chemotherapeutic agents ar......
The drug and gene co-delivery stragegy has emerged to yield promising results in cancer therapy,because it could enhance......
Magnetic/fluorescent hybrid PLGA nanoparticles for doxorubicin/VEGF siRNA co-delivery and tumor imag
Doxorubicin (Dox) as a traditional chemotherapy drugs,have significant side effects,such as cardiotoxicity,mucositis,mye......
A facile construction of pH-sensitive shell-sheddable supramolecular nanoassembly codelivery antican
A facile method to engineering a novel pH-sensitive shell-sheddable supramolecular nanocarrier was devised in this study......
Co-delivery of Anti-miR-181b and Doxorubicin by Multifunctional Gold Nanocages for Enhanced Anti-Tum
Co-delivery of nucleic acids and chemotherapeutics has the potential to efficaciously treat human diseases via their syn......
Co-delivery of doxorubicin and P-gp siRNA into human breast cancer cells by functionalized PLGA nano
Multidrug resistance (MDR) is a major impediment to the success of cancer chemotherapy.One of the effective approaches t......
Synergistic therapeutics have been demonstrated as means for effective tumor therapy,while the co-loading of cargoes wit......
Nanoscale stimuli-responsive systems for gene and drug delivery have recently received tremendous attention[1].The syste......
Co-delivery of Multiple Drugs via a Polymer-(Demethylcantharidin-Platinum) Conjugate for Enhanced Ca
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Dual-sensitive charge-conversional polymeric prodrug for efficient co-delivery of demethylcantharidi
Tumor is a complicated system,and tumor cells are typically heterogeneous in many aspects[1].Polymeric drug delivery nan......
Co-delivery of doxorubicin and triptolide with reduction-sensitive lipid-polymer hybrid nanoparticle
Co-delivery is a promising strategy to overcome the limitations of single chemotherapeutic agent in cancer treatment.Des......
Objective Combination treatment through simultaneous delivery of anticancer drugs and gene with nano-formulation has bee......
The combination of chemotherapeutic agents with gene therapy offers a great chance for cancer treatment.In this work, qu......
PH-and redox-responsive nanoparticles containing charge-reversible pullulan-based shell and disulfid
Objectives: A novel pH-and redox-responsive nanoparticle system was designed based on charge reversible pullulan derivat......
Reconstituted high density lipoprotein(rHDL)represents an excellent biomimetic tool for targeted delivery of chemical/bi......
Bmi1 siRNA Conjugated Lipid-Coated Cisplatin Nanoparticles Inhibit Growth of Hepatocellular Carcinom
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Low-density lipoprotein-coupled N-succinyl chitosan lipoic acid micelles co-delivering siRNA and Pac
Objective: To increase targeting effect and reverse the multiple drug resistance(MDR) on cancer cells by building and in......
Multidrug Resistance Reverse by Co-delivering Elacridar and Doxorubin using a Dual Sensitive Nano-ca
Elacridar (ELC), a reversal agent of multidrug resistance (MDR), has been demonstrated as an excellent P-glycoprotein (P......
Amphiphilic Copolymeric Micelles for Doxorubicin and Curcumin Co-delivery to Reverse Multidrug Resis
Development of multidrug resistance against chemotherapeutic drugs is one of the major obstacles to successful cancer th......
Quercetin and Doxorubicin Co-encapsulated Biotin Receptor-targeting Nanoparticles for Minimizing Dru
The combination of a chemotherapeutic drug with a chemosensitizer has emerged as a promising strategy for cancers showin......
Traditional therapy aimed at changing tumor microenvironment makes efforts on reducing tumor vessel density to control i......
Study on low density lipoprotein coupled N-succinyl chitosan polymeric nanoparticles co-delivering s
Objective: To increase targeting effect and reverse the multiple drug resistance(MDR) on cancer cells by building and in......
Co-delivery of calreticulin DNA and doxorubicin by mPEG-LPEI-PCL micelle to exert synergistic antica
Combination of chemotherapy with gene therapy is a promising strategy for cancer treatment.The aim of the current study ......
Enhanced Chemotherapy Efficacy by Co-delivery of shABCG2 and Doxorubicin with a pH-responsive Charge
In this study,a graphene oxide(GO)-polyethylenimine(PEI)-polyethylene glycol(PEG)graft copolymer wassynthesized.DOX load......
Multi-agent therapy plays a critical role in cancer treatment,and it can cooperatively prohibit cancer development maxim......
DNA origami directed in-situ combination of chemotherapy and gene therapy with enhanced antitumor ef
Malignant tumor is one of the most serious diseases that affect human health.As patients with long-term chemotherapy,mul......
Gold Nanorods-Based platforms for Co-Delivery of Doxorubicin and siRNA and Light-Driven Therapy in P
Within the nanoparticle family,AuNRs with light scattering,localized surface plasmon resonance (SPR),photothermal effect......
Carrier-free nanoparticles based on self-assembly between doxorubicin and chlorine e6 for synergisti
Despite remarkable progress in chemotherapy,high drug loading efficiency for clinical use and enhanced/synergistic a......
多项研究揭示SDF-1/CXCR4是与癌症转移最相关的趋化因子通路之一,因此靶向CXCR4的siRNA能够改善高转移性癌症治疗效果,尤其将其与......
目的利用聚乙二醇(PEG)修饰的阳离子脂质体实现和厚朴酚与siRNA的共递送以改善肿瘤治疗效应。方法利用薄膜分散法制备聚乙二醇修饰......
共递送抗癌药多柔比星和基因治疗肿瘤可以产生协同治疗作用,提高治疗效果,降低毒性以及克服多柔比星引起的多药耐药性。共递送抗癌......
,Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic b
Breast cancer is the most vicious killer for women,and tumor metastasis is one of the leading causes of breast cancer th......
,Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin
To achieve synergistic therapeutic efficacy and prevent cancer relapse,chemotherapy and immunotherapy have been combined......
A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole an
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
DRUG AND PLASMID DNA CO-DELIVERY NANOCARRIERS BASED ON ABC-TYPE POLYPEPTIDE HYBRID MIKTOARM STAR COP
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Alginate-based complex fibers with the Janus morphology for controlled release of co-delivered drugs
Hydrogels are soft materials consisting of a three-dimensional network of polymer chains.Over the years,hydrogels with d......
合成了聚乙烯亚胺接枝二茂铁(PEI-Fc)两亲聚合物,采用水包油法制备包埋疏水性抗癌药阿霉素(DOX)的载药胶束,并利用胶束表面正电荷的PEI......