ChIA-Pet相关论文
Predicting lncRNA-protein complexes with ChIA-PET data by 3CPET, a hierarchical Dirichlet process ba
Long non-coding RNAs (lncRNAs) are non-coding transcripts longer than 200 nucleotides.More and more studies have found t......
Background:Long-range chromatin interactions are spatially and temporally maintained and established through a set of pr......
Characteristic arrangement of nucleosomes is predictive of chromatin interactions at kilobase resolu
High throughput chromosome conformation capture technologies such as Hi-C,have made it possible to survey the 3D gen......
Many enhancers regulate their target genes via long distance interactions.High-throughput experiments like ChIA-PET ......
Analysis of gene location relative to chromosome loops and topological chromosome domains by ChIA-PE
Several technologies based on chromatin immunoprecipitation (ChIP) have been developed to study the binding of transcrip......
生物个体的新陈代谢离不开基因复杂的转录调控和遗传机制。随着高通量测序技术的快速发展,基因组序列的成功测序使得我们能够进一......
真核生物的染色体如何发生复杂构象变化并组织成复杂的高级结构,仍是一个研究热点。染色体的这些结构特征和构象变化可通过了解染......
特定DNA调控元件之间的长距离染色质接触在基因表达调控中起着关键作用,在理解信号网络和细胞状态时,必须对这些三维(3D)染色质结......
近20年来,研究者们通过大规模DNA测序,在基因组、转录组和表观基因组方面获得了大量的信息,这些信息为人类基因组中的功能元件和相......
人类基因组测序完成已有十多年.但是,基因组信息如何指导基因在特定空间和时间表达的机理仍有待阐明."结构决定功能"是认识自然规......
玉米是全球种植面积与产量均列首位的重要作物,对其基因组的深度解析具有重要意义。本论文由两部分工作组成:采用ChIA-PET研究的玉......
随着人类基因组计划、ENCODE计划、千人基因组计划的顺利实施与完成,基因组学研究的重点已经从揭示生物体的遗传信息和密码学转变......
基因组的空间结构与细胞功能密切相关,例如基因表达与调控、细胞分化与鉴定、组织发育等。线性DNA长度约为2米,它被高度填充在染色......
