Mitogen-activated protein kinases (MAPKs) are the main regulators of cellular proliferation, growth, and survival in phy......

目的:观察荜茇酰胺(PLM)对人小细胞肺癌耐药株H446/DDP细胞顺铂(DDP)耐药性的逆转作用,并探讨其可能的分子机制。方法:采用浓度梯......

目的：探讨V—ATPase在食管鳞癌中的表达及其病理分级、TNM分期中的差异性；检测相应癌组织对化疗药物的敏感性，分析其与V—ATPase表达......

Gastric cancer(GC) is the fourth most common cancer worldwide and ranks second in global cancer mortality statistics. Pe......

Epithelial-to-mesenchymal transition(EMT) is defined as the transformation of an epithelial cell into a spindle cell wit......

Genetic interactions are functional crosstalk among different genetic loci that lead to phenotypic changes,such as healt......

目的：根据肿瘤干细胞学说理论，探讨胰腺癌耐药的新机制。方法：通过胰腺癌肿瘤干细胞表面标记途径和侧群（side population，SP）细胞途径，分......