EVODIAMINE相关论文
吴茱萸碱、吴茱萸次碱、去氢吴茱萸碱是吴茱萸中主要的生物碱类成分.为研究吴茱萸主要生物碱成分在大鼠脑脊液中的代谢和在脑组织......
Objective: To investigate the effects of evodiamine (Evo), a component of Evodiaminedia rutaecarpa (Juss.) Benth, on car......
Evodiamine,has therapeutic potential in drug resistance by targeting HIF-1α in hypoxic microenvironm
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Inhibitiory effect of evodiamine on angiotensin Ⅱ-induced proliferation in rat vascular smooth muscl
Aim: To investigate the effects of evodiamine (Evo), a component of Evodiarutaecarpa (Juss) Benth, on vascular smooth mu......
The purpose of this study was to evaluate the increased physicochemical characterization,in vitro release,enhanced absor......
Objective: Epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI)therapy is considered as one of the most ......
Evodiamine-inspired Dual Histone Deacetylase 1(HDAC1)and Topoisomerase 2(Top 2)Inhibitors with Poten
A great challenge in multi-targeting drug discovery is to identify drug-like lead compounds with therapeutic advantages ......
Evodiamine is one of the most important components of Evodia rutaecarpa,which has been used for a long time in tradition......
目的 建立同时测定复方吴茱萸软膏中吴茱萸碱和吴茱萸次碱含量的方法.方法 采用HPLC法,色谱柱为Agilent HC-C18(250 mm×4.6 mm,5......
吴茱萸碱是一种天然存在的吲哚生物碱，也是中药吴茱萸的主要生物学活性成分。当提及吴茱萸碱的药理学活性时人们往往关注其在肿瘤、......
目的:探讨吴茱萸碱对心肌细胞缺血损伤的保护作用.方法:培养H9c2心肌细胞,缺氧24 h造成心肌细胞损伤模型,给予不同浓度(0.1,1,5,10......
目的 吴茱萸碱和吴茱萸次碱是中药吴茱萸中的主要生物碱成分,二者可以通过激活辣椒素受体(TRPV1)释放CGRP达到舒张血管降低血压的......
Evodiamine is an indole quinazoline alkaloid with anti-tumor activity,which may be developed into a drug for the treatme......
目的:研究吴茱萸生物碱含药血清的抗菌活性。方法:以Dimonsil C18(2)色谱柱(150 mm×4.6 mm,5μm)为固定相,水-甲醇-乙腈(42∶20∶......
目的:通过建立的高效液相色谱法对吴茱萸及其炮制品中吴茱萸碱、吴茱萸次碱和柠檬苦素3个指标性成分含量进行测定,并进行对比分析.......
Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the g
Objective:High-fat diet is one of the main risk factors that disrupt the balance of gut microbiota,which eventually will......
Evodiamine improves congnitive abilities in SAMP8 and Appswe/PS1△E9 transgenic mouse models of Alzhe
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Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with
A great challenge in multi-targeting drug discovery is to identify drug-like lead compounds with therapeutic advantages ......
Combination of Evodiamine with Berberine Reveals a Regulatory Effect on the Phenotypic Transition of
Objective Transdifferentiation exists between stromal cells or between stromal cells and cancer cells. Evodiamine and be......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
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Evodiamine induces extrinsic and intrinsic apoptosis of ovarian cancer cells via the mitogen-activat
OBJECTIVE: To explore the effects of evodiamine on ovarian cancer cells and the mechanisms underlying such effects.METHO......
目的探讨吴茱萸碱对血管紧张素Ⅱ(AngⅡ)所致大鼠血管平滑肌细胞(VSMCs)增殖周期的影响,并探讨其机制。方法利用组织块贴壁法培养......
目的采用LC-ESI-MS/MS法同时测定大鼠血浆中的吴茱萸碱、吴茱萸次碱和吴茱萸内酯,并研究这3种活性物质在大鼠体内的药动学特征。方......
目的制备水包油型复方吴茱萸碱纳米乳,并考察其体外释放和大鼠在体肠的吸收情况。方法采用透析法考察复方吴茱萸碱纳米乳的体外释......
Simultaneous Analysis of Thirteen Bioactive Components in Evodia rutaecarpa and Its Varieties by HPL
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Regulatory effect of evodiamine on the malignant biological behaviors and Wnt/β-catenin signaling pa
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective:To explore the proliferation inhibition and apoptosis-inducing effect of evodiamine in human gastric cancer SG......
目的:研究吴茱萸碱和吴茱萸次碱微透析探针体外回收率及传递率与流速、药物浓度之间的关系。方法:浓差法(正、反向透析法)考察流速......
Simultaneous Analysis of Thirteen Bioactive Components in Evodia rutaecarpa and Its Varieties by HPL
Objective To control the quality of Evodia rutaecarpa better. Methods An HPLC-DAD-MS/MS method was established for the r......
目的:溃疡性结肠炎是诱发炎症性相关结直肠癌的最主要病因。前期研究表明,吴茱萸碱对于氧化偶氮甲烷/葡聚糖硫酸钠诱导的小鼠炎症......
目的吴茱萸碱和吴茱萸次碱是中药吴茱萸中的主要生物碱成分,二者可以通过激活辣椒素受体（TRPV1）释放CGRP达到舒张血管降低血压的作用......
采用HPLC法测定了湖北阳新县所产吴茱萸在不同提取方法下吴茱萸碱和吴茱萸次碱的含量。结果表明,在流动相为水-甲醇-乙腈（44∶20∶3......
目的建立一种同步测定吴茱萸超微速溶饮片中吴茱萸碱，吴茱萸次碱及柠檬苦素含量的高效液相色谱方法。方法采用HypersilODS2Cls柱（4．6m......
建立了吴茱萸中吴茱萸碱和吴茱萸次碱的反相高效液相色谱法，并用该法测定了３４种不同产地及不同炮制方法吴茱萸中吴茱萸碱和吴茱萸次碱......
目的观察吴茱萸碱对胃癌细胞增殖、侵袭的影响,并探讨其机制。方法采用不同浓度的吴茱萸碱处理人胃癌细胞SGC7901,用软琼脂集落培......
目的明确吴茱萸碱对血管紧张素Ⅱ（AngⅡ）诱导血管平滑肌细胞（VSMC）增殖的抑制作用及对细胞外信号调节激酶-1（ERK-1）和丝裂原活化蛋白激酶......
目的:采用高效液相色谱法测定黄连的炮制品萸黄连中吴茱萸碱的含量,以探索萸黄连的质量控制.方法:采用KromasilC18,以乙腈-水(44:5......
目的：用肠外翻模型研究制吴茱萸提取物不同剂量在大鼠不同肠段的体外肠吸收特征及其与P-gp的关系。方法：采用大鼠肠外翻模型，以吴茱萸......
本文研究吴茱萸碱对胃癌细胞SGC-7901凋亡的影响,用不同浓度的吴茱萸碱处理SGC-7901细胞,采用MTT法评价吴茱萸碱对SGC-7901细胞增......
目的建立同时测定萸黄连中吴茱碱和吴茱萸次碱含量的高效液相色谱法。方法采用Agilent Zobax SB C18柱(250 mm×4.6 mm,5μm),......
利用响应面法对吴茱萸中吴茱萸碱和吴茱萸次碱的提取工艺进行优化。以吴茱萸碱和吴茱萸次碱得率为响应值,通过单因素实验和Box-Beh......
[目的]建立HPLC法同时测定泡吴茱萸中吴茱萸碱、吴茱萸次碱和柠檬苦素含量的方法。[方法]采用Agilent 5 TC-C18(2)(250 nm×4.......
[摘要] 目的 建立超微戊己丸中吴茱萸碱和吴茱萸次碱的含量测定方法。 方法 采用Kromasail C18色谱柱（250mm×4.6mm，5μm），流动相为流......
用薄层扫描法测定了小儿腹泻贴膏剂中吴茱萸碱和吴茱萸次碱俯含量。灵敏度中，回收率分别为吴茱萸碱１００．４％，ＲＳＤ２．８３％，吴茱萸次碱１０１．６％，ＲＳＤ２．３１％。......
目的:研究超临界流体萃取(SFE)吴茱萸中吴茱萸碱和吴茱萸次碱的提取工艺,并用高效液相色谱法(HPLC)测定吴茱萸碱和吴茱萸次碱的含......
从吴茱萸的果实中分离得到晶形完美的单体化合物,经核磁测试鉴定该化合物为吴茱萸碱,通过X-单晶衍射解析了该化合物的空间结构、键......
目的研究黔产吴茱萸的化学成分。方法利用各种色谱技术进行分离纯化，根据化合物的理化性质和光谱数据进行结构鉴定。结果从黔产吴茱......
建立了反相高效液相法（ＲＰ－ＨＰＬＣ）测定吴茱萸碱及吴茱萸次碱的定量方法，主要色谱条件为：色谱柱Ｐｈｅｎｏｍｅｎｅｘ－ＯＤＳ；流动相为：水－乙腈－冰乙酸－四氢呋喃（１００：９０：０．２：２）（ｐＨ＝５．０）；流速为１．０ｍｌ／ｍｉｎ；检测波长２５４ｎｍ；线性......
