GLUCURONIDATION相关论文
The isoform-specific and time-dependent of luteolin glucuronidation via human UGTs in vitro and in s
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Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Salvianolic Acid A, Salvianolic Aci
Bilirubin-related adverse reactions (e.g., jaundice and hyperbilirubinemia) induced by certain herbal injections rich in......
Hepatic toxicity and toxicokinetics of emodin, an anthraquinone component from Polygonum multiflorum
Heshouwu, the tuberous root of Polygonum multiflorum Thunb, is widely used as traditional Chinese herbal medicine for th......
UGT2B7 is the most important enzyme in emodin glucuronidation: genome-wide association and RNA-seq s
Background: Emodin (6-methyl-1,3,8-trihydroxyanthraquinone), a traditional medicine for purgation, was shown to possess ......
New insights into SN-38 glucuronidation: evidences for the important role of UDP-glucuronosyltransef
Glucuronidation of SN-38 serves as an important metabolism pathway in determining the toxic effects of irinotecan....
UDP-glucuronosyltransferase (UGT) 1A1-catalyzed glucuronidation is an important elimination pathway of flavonoids, and m......
Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of
Bilirubin-related adverse reactions (ADR, e.g., jaundice and hyperbilirubinemia) induced by herbs rich in certain polyph......
Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Danshen (Salvia Miltiorrhiza) injec
In recent years, bilirubin-related adverse reactions (e.g., jaundice and hyperbilirubinemia) induced by Danshen (Salvia ......
Metabolites study of salvianolic acid L, a novel phenolic acid constituent from Salvia miltiorrhiza,
AIM To identify salvianolic acid L (SAL) metabolites in rats.METHODS Bile duct of wistar rats (n =6, male)was cannulated......
Rutaecarpine is an alkaloid of Evodia rutaecarpa which is traditionally used to treat human diseases.Rutaecarpine has be......
Baicalein (5,6,7-trihydroxyflavone) is one of the typical representatives of flavonoids, which isolated from Scutell......
综述了葡萄糖醛酸轭合反应在药物代谢转化中的作用研究进展。论述了催化药物葡萄糖醛酸轭合反应的葡萄糖醛酸转移酶（UDP-Glucuronos......
目的 了解尿苷二磷酸葡萄糖醛酸转移酶(UGT) 2B7 mRNA和蛋白在子宫内膜癌组织中的表达及临床意义.方法 分别采用Real-time PCR和免......
Stereoselective urinary excretion of S-(-)- and R-(+)-propranolol glucuronide following oral adminis
AIM: To study the stereoselectivity of phase Ⅱglucuronidation metabolism of side-chain propranolol in Chinese Hah popul......
Glucuronidation is the dominating in-vivo metabolism pathway of herbacetin:elucidation of herbacetin
OBJECTIVE To map a comprehensive metabolic pathway of herbacetin in rats,specifically,to elucidate the biotransformation......
尿苷-5’-二磷酸葡萄糖醛酸转移酶(UGT)是药物II相代谢反应最主要的酶,通过催化葡萄糖醛酸与内源性或外源性化学物质发生葡萄糖醛......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的建立黄芩素葡萄糖醛酸化代谢产物B-7G和B-6G的高效液相色谱方法。方法用Kromasil C18柱(4.6 mm×150 mm,5μm),柱温40℃,流动......
Stereoselective urinary excretion of S-(-)- and R-(+)-propranolol glucuronide following oral adminis
AIM: To study the stereoselectivity of phase Ⅱglucuronidation metabolism of side-chain propranolol in Chinese Hah popul......
The glucuronide metabolites of benproperine were synthesized from mono-hydroxylate metabolites of benproperine that were......
目的了解尿苷二磷酸葡萄糖醛酸转移酶（UGT）287mRNA和蛋白在子宫内膜癌组织中的表达及临床意义。方法分别采用Real—timePCR和免疫组......
目的：研究不同剂量染料木黄酮及其葡萄糖醛酸化代谢产物在大鼠尿中的排泄动力学。方法：将染料木黄酮制成混悬液，按6．25、12．5、50mg......
目的建立人UGTlA3催化黄酮类化合物定量构效关系，考察不同结构参数对葡醛酸结合反应的影响。方法采用半经验量子化学计算法MOPAC-AM......
AIM: To clone the cDNA of UGT1 A9 from a Chinese human liver and establish the Chinese hamster lung (CHL) cell line expr......
Androgen—independent growth in LNCaP cell lines and steroid uridine diphosphate—glucuronosyltransfer
Aim:To investigate the mechanism of adrogen-independent growth of prostate cancer after androgen ablation in LNCaP cells......
Objective:To explore the glucuronic acid metabolism of acacetin in human liver and intestinal microsomes to better chara......
人葡糖醛酸基转移酶（UGT）同工酶在黄酮类化合物Ⅱ相代谢反应中呈重要的作用。本综述总结了近年来国内外学者对黄酮类化合物Ⅱ相代谢......
目的旨在了解银杏黄酮山奈酚代谢的有关酶系及酶动力学参数.方法采用苯巴比妥(PB)、地塞米松(DEX)、β-萘黄酮(BNF)和地非三唑(DIP......
