LIGASE相关论文
Epithelial-mesenchymal transition (EMT) is critical for the conversion of early stage tumors into invasive malignancies.......
MYB106 is a negative regulator and a substrate for CRL3^(BPM) E3 ligase in regulating flowering time
Flowering time is crucial for successful reproduction in plants, the onset and progression of which are strictly control......
The RING finger ubiquitin E3 ligaseOsHTAS enhances heat tolerance by promoting H2O2-induced stomatal
Heat stress often results in the generation of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2), which......
Association between MYO9B rs962917 and rs1545620 gene polymorphism and clinical characteristic of in
Objective To investigate the association between MYO9B rs962917 and rs1545620 gene polymorphism and clinical pathologica......
<正> Since the availability of T4 RNA ligase, a great progress has been made in fields of synthesis of polynueleotides. ......
<正> Since T4-RNA ligase was first discovered by Silber et al. in 1972, it has been extensively used as an important too......
Virion infectivity factor(Vif) is one of the six accessory proteins of HIV-1 and is necessary for viral infectivity. Hum......
In this study, we selected 10 susceptible SNPs loci to investigate their contribution to susceptibility to type 2 diabet......
This paper deals with the synthesis of nonanucleotide AGDCGGDAG_p of the dihy-drouridine(D)loop of yeast alanine transf......
Relationship between glucokinase gene 6 tag single nucleotide polymorphism sites and type 2 diabetes
Objective To investigate the relationships between glucokinase(GCK)gene 6(tag single-nucleotide polymorphisms,tag SNPs)s......
Medulloblastoma is the most common malignant pediatric brain tumor. In mice, Ptcl haploinsufficiency and disruption of ......
Comparison of ligase detection reaction and real-time PCR for detection of low abundant YMDD mutants
AIM: To compare the ligase detection reaction (LDR) and real-time PCR for detection of low abundant YMDD mutants in pati......
AIM: To establish a multiple detection method based on comparative polymerase chain reaction (cPCR) and ligase detection......
Effect of transfected angiotensinⅡ receptor anti-sense nucleotide on the growth of cardiomyocytes in
Objective:To evaluatetheeffectof transfectingangiotensinⅡreceptor(AT1)anti-sensenucleotide(AT1A)on theexpressionof subt......
AIM:To construct a recombinant E.coli strain that wouldhighly express the proinflammatory outer membraneprotein of huma......
To establish a cell line for stable expression of human beta-defensin 3 (hBD3). Methods Full length cDNA of hBD3......
Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: Roles of cyclic AMP and p
AIM: Fatty acid-CoA ligase 4 (FACL4) is an arachidonate-preferring enzyme which has been shown to be up-regulated in hum......
MAP kinase-interacting kinase-2 (Mnk2) is one of the downstream kinases activated by MAP kinases. It phosphorylates the ......
HUMAN PAPILLOMAVIRUS TYPE 16 L1 PROTEIN CAN BE EXPRESSED IN LIVE ATTENUATED SHIGELLA FLEXNERI 5A STR
Objective Attenuated strains of Shigella are attractive live vaccine candidates for eliciting mucosal immune responses w......
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteobl
Subject Code:H06 With the support by the National Natural Science Foundation of China,a study by the research group led ......
We previously found that HPV16 E6 causes the degradation of the tumor suppressor protein TSC2, resulting in the phosphor......
2008年10月28日,中国科学院遗传与发育生物学研究所谢旗博士实验室在PlantJ在线发表题为“RKP,a RING finger E3 ligase induced b......
目的研究碱基切除修复途径(base excision repair,BER)关键因子PARP1、ligase3和XRCC1在Ku70缺失的条件下与DNA双链断裂(double-st......
据2013年6月4日张召(Dev Cell,2013 Jun 4.doi:10.1016/j.devcel.2013.05.006)报道,中国学者发现,Ter94复合物选择K11连接形式泛素......
It has been well established that eytotoxic T lymphocytes(CTLs)are responsible for the mediation of host immune response......
Tripartite motif 33(TRIM33), a member of the transcription intermediate factor 1(TIF1) family of transcription cofactors......
据中国农科院植保所通报,近期,该所所长周雪平教授领衔的作物有害生物功能基因组研究创新团队在双生病毒与植物互作方面取得新的研......
2016年12月15日,国际学术期刊Cell Host&Microbe发表了中国科学院上海生命科学研究院植物生理生态研究所何祖华研究组题为An E3Ubi......
The synthesis of Leu-enkephalin gene by an alternative approach was described in thispaper. The sequence of the synthet......
By a combination of chemical and enzymatic methods, small oligonucleotides with lengths varying from 2 to 8 nucleotides......
RNA ligase in eukaryotic mammalian cells was studied by using mouse brain and livercell extracts as enzyme sources and ......
A thorough study on the reaction of 32_pN_p with 14 dinucleoside monophosphates including U_pI and C_p m~1I has been re......
Expression and sub-cellular localization of leucine-rich repeats and immunoglobulin-like domains are
The current study investigated correlations between the expression of leucine-rich repeats and immunoglobulin-like domai......
S-phase kinase-associated protein 2 (Skp2) belongs to the F-box protein family.It is a component of the SCF E3 ubiquitin......
Supported by the National Natural Science Foundation of China,the groups of Dr.Liu Jiang at Beijing Institute of Genomic......
With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology,Prof.Che......
The Rictor/mTOR complex plays a pivotal role In a variety of cellular functions including cellular metabolism,cell proli......
With the support of the National Natural Science Foundation of China,the research team led by Prof.Mao Xinliang(毛新良)f......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Glioma is the tumor with the highest incidence in the brain,and it is eager to seek new and efiective treatment.The inte......
Protein ubiquitination is essential for diverse cellular functions including spermatogenesis.The tripartite motif(TRIM)f......
Glycogen synthase kinase-3β(GSK-3β) has been shown to attenuate DNA damage in nerve cells, thereby enhancing neuronal ......
目的研究睾酮对地塞米松所致大鼠骨骼肌萎缩的治疗作用以及对泛素连接酶表达的影响。方法40只雌性SD大鼠随机均分为对照组、地塞米......
目的构建结核分枝杆菌H37Rv的ligC原核表达载体,并进行表达纯化及酶学测定。方法以结核分枝杆菌H37Rv基因组DNA为模板,PCR法扩增ligC......
发展了一种基于连接酶介导的诱导荧光共振能量转移技术用于基因点突变的准确快速检测方法.针对特定突变位点设计的核酸探针,当与模板......
Ovarian cancer(OC)is the sixth most common cancer and the seventh cause of death from cancer in women.The etiology and t......
Characterization of a Novel RING-Type Ubiquitin E3 Ligase GhRING2 Differentially Expressed in Cotton
The ubiquitin-proteasome proteolysis pathway is responsible for the degradation of abnormal and short-lived proteins to ......
Obesity is a serious health problem of our time. Dysfunction of adipogenesis, the differentiation of adipocytes, is a ha......
目的:利用慢病毒干涉下调内源性RNF31表达,研究NF-κB通路的活化及对细胞凋亡的影响。方法将人RNF31的shRNA片段克隆到慢病毒表达载......