MULTIDRUG相关论文
Comparative Study of the Genetic Diversity, Antimicrobial Resistance, and Pathogenicity of Aeromonas
Objective This study was performed to compare the genetic diversity,virulence,and antimicrobial resistance of Aeromonas ......
Prevalence of Adverse Drug Reactions to Second Line Anti Tuberculosis Drugs in Nigeria: A Cross-Sect
<b><span>Introduction:</span></b><span></span><b> </b><span>Multidrug</span><span><span><span style=“font-family:;” “......
<b><span style=\"font-family:Verdana;\">Background and Purpose: </span></b><i><span style=\"font-family:Verdana;\......
The emerging nanotechnology-based drug delivery holds tremendous potential to deliver chemotherapeutic drugs for treatme......
比较轮环藤碱（Ｃｙｃ）、海岛轮环藤碱（Ｉｎｓｒ）和海岛轮环藤酚碱（Ｉｎｓｎ）与维拉帕米（Ｖｅｒ）体外调节多药耐药性（ＭＤＲ）的作用．方法：细胞毒试验采用ＭＴＴ法，细胞内阿霉素（Ｄｏｘ）积累采用荧光......
采用转染上人类ＭＤＲ１基因，对长春花碱及阿霉素具有交叉耐药性的鼠黑色素瘤细胞株对从鼓槌石斛中分得的二个氢芪类化合物毛兰素及鼓槌素......
To investigate the relationship between p38 mitogen-activated protein kinase (p38MAPK)and cell apoptosis during the pacl......
Stenotrophomonas maltophilia,an emerging pathogen in newborns:Three case reports and a review of the
BACKGROUND Stenotrophomonas maltophilia(S.maltophilia)is a rare cause of neonatal sepsis with significant morbidity and ......
BACKGROUND:Sulfonylurea receptor 1(SUR1)and multidrug resistance protein 1(MRP1)are two prominent members of multidrug r......
目的本文拟以外排转运蛋白中的多药耐药蛋白1（multi-drug resistance protein 1,MDR1）为代表,研究其在人角膜上皮、C57BL/6小鼠角膜......
肿瘤是威胁人类健康的恶性疾病。化疗是目前临床抗肿瘤最常用的治疗方法,化疗药物具有较广的抗瘤谱。但肿瘤多重耐药的发生是导致......
目的对比研究耐药及非耐药肺癌细胞株对竹红菌乙素-光动力疗法的反应性，以及耐药肿瘤细胞对竹红菌乙素-光动力疗法及化疗药物的反应......
Synergistic anticancer effect of exogenous wild-type p53 gene combined with 5-FU in human colon canc
AIM To investigate the anticancer effect of a recombinant adenovirus-mediated p53(r Ad-p53) combined with 5-fluorouracil......
The gastrointestinal barrier is constantly exposed to numerous environmental substrates that are foreign and potentially......
目的 探讨Ｂｃｌ－２蛋白与Ｐ－糖蛋白在胃癌发生、发展和耐药性产生中的作用以及二者间的相互关系。方法 应用免疫组化ＳＰ法检测胃癌组织中的Ｂｃｌ－２蛋白......
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<span style="font-family:""><span style="font-family:Verdana;">Thermophilic </span><i><span style="font-family:Verdana;"......
ＥＳＴＡＢＬＩＳＨＭＥＮＴＯＦＣＲＩＴＥＲＩＡＦＯＲＭＥＡＳＵＲＩＮＧＭＤＲ１ＧＥＮＥＥＸＰＲＥＳＳＩＯＮＬＥＶＥＬＩＮＢＲＥＡＳＴＣＡＮＣＥＲＢＹＲＴＰＣＲＬｉｕＸｉａｏｑｉｎｇ刘晓晴ＳｏｎｇＳａｎｔａｉ宋三泰ＳｈｉＣｈｅｎｇｈｕａ石成华ＸｕＪ.........
REGULATION OF EXPRESSION OF P-GLYCOPROTEIN AND GST BY MULTIDRUG-RESISTANT REVERSORS IN ADM-SENSITIVE
客观：为了在 ADM 敏感、 ADM 抵抗的人的白血病的房间线和 KB 房间从三 reversors 调查 p-glycoprotein (PgP ) 和 GST 表示的规定，......
REGULATION OF EXPRESSION OF P-GLYCOPROTEIN AND GST BY MULTIDRUG-RESISTANT REVERSORS IN ADM-SENSITIVE
客观：为了在 ADM 敏感、 ADM 抵抗的人的白血病的房间线和 KB 房间从三 reversors 调查 p-glycoprotein (PgP ) 和 GST 表示的规定，......
Objective: A single mechanistic pathway cannot explain the genesis of drug resistance in cancer. Drug resistance in canc......
目的分析急性心肌梗死患者肺部感染多药耐药菌的危险因素及病原菌分布,为临床防治提供依据。方法选取2015年5月-2016年5月医院就诊......
目的DNA微阵列芯片法（博奥）检测临床痰标本中耐多药结核分枝杆菌相关基因突变，评价诊断耐多药结核病（MDR—TB）的应用价值。方法对涂阳肺......
目的构建并鉴定表达MDR-1小干扰RNA的慢病毒载体系统并检测其对于喉癌多药耐药细胞系（LSC-1/TAX）多药耐药表型的逆转效果。方法根据M......
【正】BACKGROUND: Cholecyst cholesterol lithiasis is a common disease of the digestive system; however, the cause of lit......
JNK1,JNK2,and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular ca
BACKGROUND:Multidrug resistance(MDR)is extremely common in hepatocellular carcinoma(HCC)and is a major problem in cancer......
Apoptosis of tumor cells have become a newstandard for chemotherapy. It is useful to demonstrateinduction of apoptosis i......
客观：为了由人的野类型的 p53， GM-CSF 和 B7-1 在化疗抵抗的肿瘤房间的生物行为上探索效果，基因经由 recombinant 侵入人体气管粘膜......
Ｔｈｅｄｒｕｇｒｅｓｉｓｔａｎｔｒｅｓｅａｒｃｈｅｓｉｎｖｉｖｏａｒｅｔｈｅｂｅｓｔｗａｙｔｏｕｎｄｅｒｓｔａｎｄｔｈｅｃｏｍｐｌｅｘｉｔｙｏｆｃｌｉｎｉｃａｌｄｒｕｇｒｅｓｉｓｔａｎｃｅ．Ｓ１８０Ｒｉｓｍｕｒｉｎｅａｓｃｉｔｅｓｔｕｍｏｒｃｅｌｉ.........
EXPRESSION AND CLINICAL SIGNIFICANCE OF MULTIDRUG RESISTANCE GENE AND MULTIDRUG RESISTANCE-ASSOCIATE
客观：计算表达式和 multidrug 抵抗基因(mdr1 ) 和 multidrug 的临床的意义在尖锐白血病的联系抵抗的蛋白质(MRP ) 基因。方法：在有......
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THE CORRELATION BETWEEN THE EXPRESSION OF MULTIDRUG RESISTANCE RELATED GENE AND CELL APOPTOSIS AND C
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Objective: To understand whether verapamil (VER) resistance development in the multidrug-resistant cell line and its mec......
Objective: To investigate the expression of novel multidrugresistance transporter (BCRP gene) from human MCF-7/AdrVp bre......
目的 探讨聚集素（Clusterin）蛋白在原发性肝细胞癌（human hepatocellular carcinoma，HCC）中的表达及与多药耐药的关系。方法 采用免疫组......
凋亡或程序性细胞死亡是正常和瘤性淋巴细胞自稳调控的重要机制，众多的细胞凋亡相关蛋白涉及淋巴瘤的发生，bcl-2家庭、capase-3和多......
Therapeutic efficacy and bone marrow protection of the mdr1 gene and over-dose chemotherapy with dox
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【正】BACKGROUND: Multidrug resistance proteins serve as transporters for chemical drugs in human malignancies. The obje......
目的评价司帕沙星对耐多药肺结核(MDR-PTB)的疗效.方法 104例MDR-PTB患者随机分为两组,以氧氟沙星作为对照.治疗组52例采用3SHRZE+......
目的：建立小鼠腹水型肝癌（Hca）多药耐药（MDR）模型并探讨其产生的分子机制。方法：荷Hca小鼠分为2组,每组10只。化疗组采用临床化疗FAP方案......
目的：观察人结肠癌HCT-8细胞和其耐药细胞株HCT-8/V中葡萄糖神经酰胺合成酶（GCS）的表达及意义。方法：体外培养HCT-8细胞和HCT-8/V,采用......
目的 研究P-gp、MRP、TopoⅡ在大肠癌及其相邻正常组织中表达,以明确P-gp、MRP、TopoⅡ在大肠癌自主性耐药中的作用。方法 采用Wes......
体外用ＭＴＴ法和动物移植性肿瘤模型研究棒烷肽抗生素Ｇ００６９Ａ的抗肿瘤活性，结果表明，Ｇ００６９Ａ对多药抗药性肿瘤细胞显示高度的杀伤活性，与阿霉素，长春新碱无......
ＮＴＲＯＤＵＣＴＩＯＮＭｕｌｔｉｄｒｕｇｒｅｓｉｓｔａｎｃｅ（ＭＤＲ）ｏｆｍａｌｉｇｎａｎｔｔｕｍｏｒｃｅｌｈａｓａｒｏｕｓｅｄｗｉｄｅｓｐｒｅａｄｉｎｔｅｒｅｓｔ．ＩｔｈａｓｂｅｅｎｓｈｏｗｎｔｈａｔＭＤＲｉｓｐｒｅｓｅｎｔｉｎｍａｎｙｍａｌｉｇｎ.........
AIM:To investigate the effect of the G-1666A polymorphism in the multidrug resistance related protein-1 (MRP1) on outcom......
Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients.Over the las......
Inhibitory effects of emodin, baicalin, schizandrin and berberine on hef A gene: Treatment of Helico
AIM: To investigate the inhibitory effects of emodin, baicalin, etc.on the hefA gene of multidrug resistance(MDR) in Hel......
目的探讨沙利霉素对肾癌ACHN细胞多药耐药的逆转及其机制。方法实验分为对照组、阿霉素组、沙利霉素组及阿霉素和沙利霉素联合用药......
Objective To assess the activities of biapenem against multidrug-resistant and extensively drug-resistant Mycobacterium ......
P-糖蛋白是血脑屏障上一种重要的物质外排生物转运体,参与人体多种生理病理过程,并能改变一些药物脑内动力学行为.本文综述了近年......
