POLYGLUTAMINE相关论文
Accelerating mutant huntingtin degradation by nanoparticles through autophagy-lysosome or ubiquitin-
Accelerating the clearance of intracellular protein aggregates represents a viable approach for the treatment of neurode......
,Sequestration of Glyceraldehyde-3-phosphate Dehydrogenase to Aggregates Formed by Mutant Huntingtin
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been reported to interact with proteins containing the polyglutamin......
neurodegenerative polyglutamine 疾病被不稳定的 polyglutamine 重复的扩大在各种各样的疾病蛋白质引起。尽管这些变异的蛋白质......
Emerging Concepts of Pathogenesis and Comprehensive Therapeutic Strategies for Spinocerebellar Ataxi
<div style="text-align:justify;"> <span style="font-family:Verdana;">Spinocerebellar ataxia type 3 (SCA3), also known as......
亨廷顿舞蹈病(Huntington's disease,HD)是一种由IT15基因上CAG重复序列异常扩展所致常染色体显性遗传的神经退行性疾病.HD的......
Mutant proteins containing an expanded polyglutamine tract induce cell death and cause neurodegenerative diseases. These......
Proteins containing an expanded polyglutamine tract are neurotoxins. The expanded polyglutamine proteins influence a var......
