目的:探索雷莎吉兰不对称合成的新方法。方法:以1-茚酮为原料,经“一锅法”与R-叔丁基亚磺酰胺生成亚胺,后用NaBH4还原,经柱分离得......

The most suitable bio-analytical method based on liquid-liquid extraction has been developed and validated for quantific......

It has been suggested that in patients with Parkinson’s disease (PD) metabolism of the MAO-B inhibitor selegiline to me......

Background: Antiparkinsonian pharmacotherapy represents one of the most important expenses related to Parkinson’s disea......

...

本文以1-茚酮为原料，先合成消旋体，然后经L-酒石酸拆分的方法合成（R）-N-丙炔基-1-氨基茚满（1，Rasagiline）。成本低廉，易于操作，适合工业化生......