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Intravoxel incoherent motion-Diffusion weighted imaging in evaluating the radio-sensitivity of nasop
PURPOSE:The radio-sensitivity is deem as a significant prognostic indicator for nasopharyngeal carcinomoa (NPC) and eval......
Establishment of patient-derived gastric cancer xenograft model with alteration of RTK/RAS signaling
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Angiogenesis and metastasis of prostate carcinoma in a Xenograft Model of Bone are Associated with H
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Purpose: In vivo growth rates of solid cancer cell line were retrospectively compared for examine whether they are relia......
Identification of stemness of primary retinoblastoma cells by stem cell markers,phenotype,and tumori
Objective Retinoblastoma(RB)is the most common intraocular malignancy in childhood,representing 2.5%to 4%of all pediatri......
Identifying and characterizing leukemia-initiating cells in adult B cell acute lymphoblastic leukemi
The existence and identification of leukemia stem cells in adult acute B lymphoblastic leukemia(B-ALL)remain controversi......
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Objective: To study the effect of arsenic trioxide (As2O3) on human poorly differentiated nasopharyngeal cancer cell lin......
目的:探讨生物发光成像早期监测裸鼠肺部转移瘤及定量评估肿瘤大小的价值.方法:利用生物发光成像检测含荧光素酶报告基因的人肺腺......
RNA干扰作为一种强大的分子生物学工具,通过沉默内源基因的表达来挖掘其特定的功能,从而研究几乎所有基因在正常生理过程和异常病......
Circulating microRNAs and liquid biopsy: murine xenograft models for technical validation of clinica
In oncology, liquid biopsy is applied to detect with high efficiency clinically relevant analytes, such as tumor cells, ......
Modified citrus pectin (MCP) is a carbohydrate enriched complex,which has been implicated in cancer treatment and preven......
Hemo oxygenase-1 induction in vitro and in vivo can yield pancreas islet xenograft survival and impr
Background The induced expression of heme oxygenase-1 (HO-1) in donor islets improves allograft survival.Cobalt protopor......
Background The potential application of retinoic acid receptor activators,such as all trans-retinoic acid (ATRA),for tre......
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Objective: Angiogenesis is a crucial step for tumor growth and progression. Changes of liver angiogenesis (with-out meta......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective: To study the effect of arsenic trioxide (As2O3) on human poorly differentiated nasopharyngeal cancer cell lin......
ABCG2-overexpressing S1-M1-80 cell xenografts in nude mice keep original biochemistry and cell biolo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨靶向CTNNB1短发夹RNA(shRNA)对人结肠癌Lovo细胞裸鼠移植瘤的生长抑制作用.方法 构建靶向CTNNB1的shRNA质粒载体(CTN)和......
胰腺癌是一种高度恶性的肿瘤,通过建立胰腺癌动物模型,可以更加深入地对该疾病进行研究.胰腺癌的动物模型主要包括:移植瘤模型、致......
目的通过分组筛选建立结肠癌皮下移植瘤模型的最优条件,并以此为瘤源建立结肠癌皮下移植瘤模型。方法根据细胞介质和注射部位的不......
Background The potential application of retinoic acid receptor activators,such as all trans-retinoic acid (ATRA),for tre......
Hemo oxygenase-1 induction in vitro and in vivo can yield pancreas islet xenograft survival and impr
Background The induced expression of heme oxygenase-1 (HO-1) in donor islets improves allograft survival.Cobalt protopor......
AIM: To investigate the growth suppression of adenovirus expressing p27kip1 on established esophageal tumors in nude mic......
目的利用斑马鱼胚胎建立人红白血病(HEL)细胞异种移植瘤模型,提供研究血液肿瘤的体内行为和实用药物测试的模型。方法将HEL细胞分......
目的建立5-脂氧合酶（5-1ipoxygenase，5-LOX）5-LOX siRNA转染人肝癌细胞HepG2裸鼠瘤动物模型，探讨iR-NA干扰技术在裸鼠瘤模型中应用的可......
目的观察微囊化猪脉络丛细胞脑内移植对偏侧帕金森病（PD）样猴的行为的影响。方法以海藻酸钠-多聚鸟氨酸-海藻酸钠（A-Plo-A）为材料包裹......
Advantages and limitations in the establishment and utilization of patient-derived xenografts in gas
Owing to the high genetic heterogeneity of tumors,small number of therapeutic strategies available,andfrequent presentat......
目的建立U251胶质瘤裸鼠皮下移植瘤模型,观察沉默miR-92b对U251神经胶质瘤裸鼠皮下移植瘤生长的影响。方法采用神经胶质瘤U251细胞......
目的：笔者以往的实验证明与猪抗原接触过并被CD4^＋T淋巴细胞激活的巨噬细胞能识剐、排斥猪的异种移植物，但不会排斥鼠的同种移植物，这......
目的:以人胎儿睾丸组织为供体,免疫缺陷小鼠为受体,研究人类睾丸生精细胞异种移植后的继续发育情况.方法:将26周胎儿的睾丸组织植......
AIM To assess the viability of orthotopic and heterotopic patient-derived pancreatic cancer xenografts implanted into nu......
目的 检测环磷酰胺（cyclophosphamide，CTX）对人腺泡状横纹肌肉瘤细胞株PLA-802裸鼠移植瘤生长和形态结构的影响。方法 16只裸鼠右腋皮......
目的 研究冻干化学去细胞异种神经修复大鼠坐骨神经缺损的效果.方法 48只成年雌性DA大鼠分别用4种移植物桥接大鼠1.5cm坐骨神经缺......
本研究采用同体对照的方法,随机把12只大耳白兔分成5组。兔的左侧下颌体切除后缺损处用脱蛋白猪骨移植,右侧下颌骨体切除后骨缺损......
目的:观察重组人血管抑素(recombinant human angiostatin,rhAGN)对荷人CNE-1鼻咽癌皮下移植瘤生长的抑制作用.方法:建立CNE-1鼻咽......
为了研究人类造血功能异常，学者们不断改进和发展白血病干细胞的异种移植模型。构建理想的异种移植模型，真实地模拟疾病，在研究人类白......
目的:探讨双向调控时钟基因Bmal1(brain and muscle arnt-like1)对鼻咽癌CNE1裸鼠移植瘤生长的影响及与放疗敏感性的关系。方法:采......
目的：研究高低剂量沙利度胺（Tha）联合三氧化二砷（AsT）干预SMMC7721裸鼠移植瘤生长，检测移植瘤微血管密度（MVD）和核转录因子（NF—κB）表达，观察......
目的:探讨槐耳清膏对乳腺癌MCF-7细胞裸鼠致瘤性生长抑制作用及其与调控miR-126表达的关系。方法:建立裸鼠乳腺癌MCF-7细胞皮下移......
目的探讨三氧化二砷（As2O3）和顺铂（DDP）联合应用对人乳腺癌细胞系MCF-7裸鼠移植瘤生长的抑制作用并探讨其机制。方法建立MCF-7乳腺癌裸......
目的 研制和评价一种新型小口径异种血管，为冠状动脉旁路移植术（CABG）提供新的移植血管来源。方法 将犬颈动脉采用酶-去污剂法进行脱......
[目的]探讨IL-4和IL-10在诱导异种骨移植免疫耐受中的作用.[方法]取雄性BALB/c小鼠60只(体重20～22 g)为骨移植受体,取新西兰兔1只为......
应用改良氯胺T,将<sup>131</sup>I标记于CEA单克隆抗体（McAb）,并将<sup>131</sup>I-CEA McAb注入荷人肺腺癌裸鼠体内,进行放免显像研......
将人肺实体腺癌手术切除的组织移植于裸鼠皮下,得到可连续传代的移植瘤系,其成功率为94.1％。该移植瘤潜伏期短,生长速度快,生物学性......
应用亲和层析法提纯我室自制的抗胰癌单克隆抗体4C_6,经固相氧化法标记~(131)I,腹腔注入荷人胰癌裸鼠移植瘤模型中。经体外扫描,观......
