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雄激素受体(Androgen Receptor,AR)是核受体超家族成员,以配体依赖方式介导基因转录,并招募一系列辅调节因子调控其转录,发挥其生物学功能.AR及其辅调节因子分别在前列腺癌中扮演着重要角色.
DNA损伤修复因子(ARAP1)参与调控雄激素受体AR介导的基因转录及其表观遗传学机制
【摘 要】
：
雄激素受体(Androgen Receptor,AR)是核受体超家族成员,以配体依赖方式介导基因转录,并招募一系列辅调节因子调控其转录,发挥其生物学功能.AR及其辅调节因子分别在前列腺癌中扮演着重要角色.
【机 构】
：
中国医科大学基础医学院卫生部细胞生物学重点实验室医学细胞生物学教育部重点实验室染色质生物学研究室,沈阳110001
【出 处】
：
中国细胞生物学学会2013年全国学术大会
【发表日期】
：
2013年12期
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