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  5. Polyelectrolyte complexes of poly[(2-dimethylmino) ethyl methacrylate]/chondroitin sulfate obtained

Polyelectrolyte complexes of poly[(2-dimethylmino) ethyl methacrylate]/chondroitin sulfate obtained

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：shuixi000
【摘 要】
：
Poly((2-dimethylamino) ethyl methacrylate) (PDMAEMA) is thermo-responsive with LCST in 32 -53 ℃ in aqueous media [1].Chondroitin sulfate (CS) is a important biopolymer with applications as biomaterial
【作 者】
：
Letícia C.Bonkovoski Alessandro F.Martins Ismael C.Bellettini Francielle P.Garcia Celso V.Nakamura Adley F.Rubira Edvani C.Muniz 
【机 构】
：
Grupo de Materiais Poliméricos e Compósitos-Departamento de Química-Universidade Estadual de Maringá
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
PDMAEMA chondroitin sulfate polyelectrolyte complexes release cytotoxicity 
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　　Poly((2-dimethylamino) ethyl methacrylate) (PDMAEMA) is thermo-responsive with LCST in 32 -53 ℃ in aqueous media [1].Chondroitin sulfate (CS) is a important biopolymer with applications as biomaterial because its pharmacological activity [2].Polyelectrolyte complexes (PECs) of PDMAEMA/CS were obtained for the first time and their properties were investigated by WAXS,FTIR,TGA,SEM and DLS analysis.Studies of SC release from PECs at pHs 6 and 8 were performed.Cytotoxicity assays using healthy VERO were assessed to evaluate the biocompatibility.
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