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  5. The Expression of NHERF1 Associated with Hypoxic Microenvironment and VEGF/VEGFR Signaling Activatio

The Expression of NHERF1 Associated with Hypoxic Microenvironment and VEGF/VEGFR Signaling Activatio

来源 :首都医科大学第三届研究生学术论坛 | 被引量 : 0次 | 上传用户：birdwy
【摘 要】
：
Background: Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is a scaffold protein with 358 amino acids.It is known to interact with a number of cancer-related proteins through the PDZ-Ⅰ, PDZ-Ⅱ and E
【作 者】
：
Yanan Gu Chengcheng Hao Guifang Du Wen G.Jiang Shan Cheng 
【机 构】
：
Department of Biochemistry and Molecular Biology, Capital Medical University,Beijing 100069, China;C
【出 处】
：
首都医科大学第三届研究生学术论坛
【发表日期】
：
2015年9期
【关键词】
：
NHERF1 HIF-1α VEGF/VEGFR signaling pathway NFκB Colorectal cancer 
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　　Background: Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is a scaffold protein with 358 amino acids.It is known to interact with a number of cancer-related proteins through the PDZ-Ⅰ, PDZ-Ⅱ and ERM-binding domain, and is considered a new player in CRC progression.
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