Evaluation on the anti-oxidation effects of a thermosensitive chitosan-based hydrogel loaded antioxi

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户:merry_leaf
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Antioxidin-RL,a small antioxidant peptide from the skin secretions of amphibian Rana pleuraden,consists of 14 amino acids including a single cysteine residue,which can fast scavenge free radicals and protect the skin damage against sunlight and UV[1].The highly porous thermosensitive hydrogel CS-α,β-GP,prepared with CS and α,β-glycerophosphate (α,β-GP),showed the feasibility as a 3D culture system.With interconnected pores,it could be used as a good release system for peptide drugs[2].
其他文献
Recently,oxidation-responsive polymers have been demonstrated to be promising for various biomedical applications[1].Among them,polymers containing phenylboronic acid/ester have attracted much attenti
It has been shown that dexamethasone (Dex) can induce the osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro in the presence of glycerophosphate and ascorbic acid[1].
To develop effective mucosal vaccines,two types of functional liposomes,the mannosylated lipid A-liposomes (MLLs) with a size of around 200 nm and the stealth lipid A-liposomes (SLLs) of 50 nm,both lo
Antibodies have been applied for the development of targeted gene delivery systems.Single chain antibodies targeting Herceptin and EGFR delivered siRNAs to cancer cells specifically and suppressed tum
Proteins and polysaccharides are renewable,abundant and environmental friendly natural polymers which show biocompatibility and biodegradability.Therefore,some discarded or low-cost biopolymers have b
Rose Bengal (4,5,6,7-tetrachloro-2,4,5,7-tetraiodofluorescein disodium,RB) can function as photosensitizer,which can initiate different pathways of cancer cell death including apoptosis,autophagy,and
The extract of cloudy lens and implantation of intraocular lens (IOL) is the only effective clinical treatment to cataracts.However,a common complication named after cataract,or posterior capsular opa
Supramolecular stacking of doxorubicin (Dox) on carbon-based nanomaterials for biomedical applications has been studied since the pioneering work by Liu et al.[1].Carbon dots (CDs),as a new kind of dr
Protein and peptide drugs are usually administered by injection,but the pain induced by the injection causes poor patients compliance,especially for long-term administration.Oral delivery system is ec
Multilayered tubular scaffolds have promising potential for vascular tissue engineering.Electrospinning was popularly used for scaffold fabrication to obtain fibers from nano size to micro size[1].Ant