Enhanced antitumor effect of poly(L-glutamic acid)-rose bengal conjugate nanoparticle

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户:didierda
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Rose Bengal (4,5,6,7-tetrachloro-2,4,5,7-tetraiodofluorescein disodium,RB) can function as photosensitizer,which can initiate different pathways of cancer cell death including apoptosis,autophagy,and necrosis under a specific light[1].
其他文献
Hyaluronic acid (HA) and polyethylene glycol (PEG) are widely recognized as biocompatible polymers[1],and "Click Chemistry" has the advantage of free of catalyst,no need to heat and can quickly crossl
The emerging treatment of RNA interference (RNAi) has drawn considerable attention from cancer researchers over the past decade because of their distinct ability to silence onco-related genes.However,
Although the chemical mechanisms for constructing efficient delivery carriers of nucleic acids are existing in nature as evidenced by the viral ability to deliver genetic materials into host cells of
Osteosarcoma is one of the most common types of primary malignant bone tumors in children and adolescents.
The ammonium bicarbonate (ABC) liposomes have shown to release doxorubicin (DOX) rapidly at elevated temperatures (40-42 ℃) and improve the intravenous stability at physiological temperature (37 ℃)[1]
Recently,oxidation-responsive polymers have been demonstrated to be promising for various biomedical applications[1].Among them,polymers containing phenylboronic acid/ester have attracted much attenti
It has been shown that dexamethasone (Dex) can induce the osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro in the presence of glycerophosphate and ascorbic acid[1].
To develop effective mucosal vaccines,two types of functional liposomes,the mannosylated lipid A-liposomes (MLLs) with a size of around 200 nm and the stealth lipid A-liposomes (SLLs) of 50 nm,both lo
Antibodies have been applied for the development of targeted gene delivery systems.Single chain antibodies targeting Herceptin and EGFR delivered siRNAs to cancer cells specifically and suppressed tum
Proteins and polysaccharides are renewable,abundant and environmental friendly natural polymers which show biocompatibility and biodegradability.Therefore,some discarded or low-cost biopolymers have b