【摘 要】
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D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis1, and can be allosterically inhibited by serine2.In a previous study, we develo
【机 构】
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BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chem
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D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis1, and can be allosterically inhibited by serine2.In a previous study, we developed a computational method for allosteric site prediction using a coarse-grained two-state Gō Model and perturbation3.
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