论文部分内容阅读
自杀基因hTERTp-tk/GCV系统联合中药鸦胆子对人肺癌A549细胞的杀伤效应
【机 构】
：
同济大学医学院组织胚胎学教研室 上海 200092
【出 处】
：
中国解剖学会2011年年会
【发表日期】
：
2011年1期
其他文献
甘丙肽(Galanin)是一个广泛分布于神经系统和外周组织中的神经肽。通过与其受体结合,Galanin参与调节认知、觉醒、摄食、生殖等生理过程。目前已克隆出甘丙肽受体的三种亚型,它们都属于G蛋白耦联受体(GPCR)。本研究在瞬时转染人甘丙肽2型受体(GalR2)的HEK293细胞系中给予蛋白酶体抑制剂MG132共同培养,发现GalR2在细胞中发生积累。这提示GalR2在降解过程中可能涉及泛素-蛋白
Objective For investigating whether overexpression of PDZ1 domain of PSD-95 can inhibit apoptosis in neurons induced by KA or OGD or the cerebral ischemia/reperfusion.Methods Hippocampal neurons were
Altered responses of sodium channels to cAMP-dependent protein kinase activator in an epilepsy-assoc
Familial inherited epilepsy with febrile seizures plus (GEFS+) caused by the mutation (I1656M) in SCN1A, the gene encoding the brain vohage-gated sodium channel α1 subunit, has received a considerable
Objective Generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epilepsy in infancy (SMEI) are associated with sodium channel α-subunit type-1 gene (SCN1A) mutations, although p
Spinal cord injury and regeneration related gene No 10 (SCIRR10) was first identified as an EST in our efforts of seeking genes responsive to spinal cord neuron injuries.High levels of SCIRR10 mRNA ex
Up-regulation of astroglial lipid-sensitive two-pore domain potassium channel TREK-1 in rat CNS afte
The lipid-sensitive mechano-gated TREK-1 has been shown to be predominantly expressed in the CNS.However, its regional and cellular expression under ischemic conditions remains to be determined.In thi
Objective To identify the agonists for Neuromedin U 2 receptor by using NMU2R cell line which was established by cotransfecting HEK293 with the NMU2R plasmid (NMU2R/pCDNA3.1 +) and reportergene plasmi
Objective The epileptiform activity was induced by perfusing GABAA receptor antagonist bicuculline (Bic, 30 μmol/L) in normal hippocampal slices and temporal lobe epilepsy (TLE) model was established