Effects of ursolic acid on NOX subunit and its regulation on downstream signaling pathways in rat ac

来源 :The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议) | 被引量 : 0次 | 上传用户:hawk_fox
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objective To observe the effects ofursolic acid (HA) on the express ion of NADPH oxidase(NOX) subunit and its regulation on PI3K/ Akt and P38MAPK pathways and TIMP-1,MMP-1 protein expression in rat activated hepatic stellate cells(HSC-T6), and explore the underlying mechanism.
其他文献
Background Pancreatic cancer (PC) is a deadly human malignancy.Dendritic cell (DC)-based immunotherapy with whole tumor antigens demonstrates potential efficiency in cancer treatment.Tumor RNA and tum
会议
Objective Our study is a systematic review of literature pertaining to the diagnostic value of endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasonography (EUS) and combined ERCP
会议
Objective To investigate the effects of PTEN and KAI1 double overexpression on proliferation, metastasis and radio-sensitivity in ASPC-1 pancreatic cancer cells under hypoxic condition.Methods Recombi
会议
Purpose KAI1 closely correlates with pancreatic cancer metastasis.There might be some factors that protect the cells from a proliferation inhibition by KAI1 in the solid tumors microenvironment.Hypoxi
会议
Aims The formation of antibodies to infliximab (ATIs) is closely associated with loss of clinical response and lower serum infliximab (IFX) levels in patients with inflammatory bowel disease (IBD).Qui
会议
Objective To understand the relationship between IMA/IMAR and the etiology of cirrhosis by detecting ischemia modified albumin concentration (IMA) and ischemia modified albumin/albumin ratio (IMAR) in
会议
Aims To investigate the safety and efficacy of endoscopic interventional treatment for elderly cirrhosis esophageal varices patients, providing more evidence-based clinical guidance to prevent and con
会议
Aim The current studywas aimed to determine the regulatory effect of miR-126 on expression of vascular endothelial growth factor-A (VEGFA)and its down-stream protein including protein kinase B (Akt),
会议
Background Resistance to standard Helicobacter pylori (H.pylori)treatment regimens has led to unsatisfactory cure rates in H.pyloriinfected patients.Quadruple therapies have been proposed in Maastrich
会议
Objective To investigate the effects and mechanism of nerve growth factor (NGF) on intestinal tract of mice with colitis induced by dextran sulfate sodium (DSS).Methods 40 female SPF Balb/c mice were
会议