Hemagglutinin(HA)which is essential for influenza viral infection and replication has become a target for the design of anti-influenza drugs.A novel series of oligothiophene compounds focused on the t
Chiral BINOL-based phosphoric acids are an array of privileged and bifunctional organocatalysts,the activities of which have been successfully demonstrated in a variety of organic transformations.[1]
Hybrids of metronidazole and quinolones as antimicrobial agents were developed and their bioactive assay that the newly synthesized compounds exhibited good or even stronger antimicrobial activities a
A series of novel berberine-derived benzimidazole derivatives and characterized by NMR,IR,MS and HRMS spectra.All the new compounds were screened for their antimicrobial efficacy against four Gram-pos
A series of naphthalimide nitrogen mustards as anticancer agents were developed,their structures were characterized by 1H NMR,13C NMR,IR,MS and HRMS spectra,and the single crystal of compound 4g was s
Infectious diseases caused by microbes are a serious public safety issues associated with significant mortality and health-care costs in world-wide.Hence,the development of alternative novel drugs is