【摘 要】
:
Poly (ethylene glycol) (PEG) hydrogels are widely studied and frequently used biomaterials [1,2].A significant challenge to hydrogels is to control their shape and size.Our research interests were the
【机 构】
:
Department of Materials Science and Engineering,Dalian Maritime University,Dalian 116026,China
【出 处】
:
The Third Symposium on Innovative Polymers for Controlled De
论文部分内容阅读
Poly (ethylene glycol) (PEG) hydrogels are widely studied and frequently used biomaterials [1,2].A significant challenge to hydrogels is to control their shape and size.Our research interests were the design of novel microscale hybrid hydrogel networks under bio-friendly conditions.In this work,hydrogels were fabricated by free-radical redox polymerization with PEG dimethacrylate (PEGDMA) (200 g/mol) and 2-hydroxyethyl methaerylate (HEMA) using ammonium persulfate (APS) and N,N,N,N-tetramethylethylene diamine (TEMED) as initiators and N,N-methylene bisacrylamide (BIS) as cross-linker (Fig.1).Carboxylated carbon nanotubes (CNTs) were also added to the copolymer system to improve the swelling and mechanical properties.
其他文献
Development of theranostic agent for imaging-guided photothermal therapy has been of great interest in the field of nanomedicine.In this work,our synthesized near-infiared (NIR) dye,IR825,is bound wit
Polyethylenimine (PEI) is one of the most efficient and widely studied synthetic carriers,which have been proven to be an effective transfection agent for the delivery of plasmid DNA into cells both i
The success of gene therapy greatly depends on suitable gene carriers that should provide safe,efficient and targeted delivery.Among various types of carries for gene delivery,polyethyleneimine (PEI)
Few studies concerning the conformational effect of polypeptides on drug delivery have been reported,although conformation of different polypeptides has been well-explored in the past few years.Here,w
The development of biodegradable cationic polymers for gene delivery is desirable to circumvent the drawbacks of the viral vectors [1].Additionally,degradable polymers have the potential to overcome c
Recently,hybrid nanoparticles (NPs) consisting of various materials and systems have been investigated to enhance delivery and efficacy of DNA and RNA [1].Among them,lipid-polymer hybrid nanoparticles
Cancer stem cells (CSCs),are known to be resistant to chemotherapy and radiotherapy and are associated with tumor metastasis and recurrence after treatnents,which attracted increasing attention with r
Therapeutic strategies based on the modulation of microRNA activity possess much promise in cancer gene therapy.MieroRNA-34a (miR-34a) is a mieroRNA regulated by the p53 network at transcriptional lev
The use of endoluminal metallic stents in percutaneous transluminal coronary angioplasty has become common in the treatment of arterial stenosis.Drug-eluting stents (DES) reduce stent restenosis by de
Amphiphilic polymer micelles have been extensively explored to encapsulate hydrophobic drugs for cancer drug delivery.The mostly used approaches to fabricate drug-loaded micelles are the dialysis meth