Preparation of cationic lipid layered PLGA hybrid nanoparticles for gene delivery

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：chen_chen1111

【摘要】

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【作者】

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Rajendran J C Bose Jong-Chan Ahn Arai Yoshie Seah Park Hansoo Park Soo-Hong Lee

【机构】

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Department of Biomedical Science,CHA University,Gyeonggi-Do 463-840,Republic of Korea;School of Inte

【出处】

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The Third Symposium on Innovative Polymers for Controlled De

【发表日期】

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2014年6期

【关键词】

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smart nanodelivery self-assembly cationic lipids therapeutic delivery system

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　　Recently,hybrid nanoparticles (NPs) consisting of various materials and systems have been investigated to enhance delivery and efficacy of DNA and RNA [1].Among them,lipid-polymer hybrid nanoparticles (LPHNPs) comprising a polymer core and lipid/lipid-PEG shell are one of the versatile carriers due to their complementary characteristics of both polymeric nanoparticles and liposomes [2].

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Preparation of cationic lipid layered PLGA hybrid nanoparticles for gene delivery

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