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  5. Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats

Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：o8o8kid
【摘 要】
：
Aim: Intrahepatic cholestasis of pregnancy (ICP) is a liver disease which may occur in the third trimester of pregnancy.The etiology and pathogenesis of ICP is thought to be closely related to bile ac
【作 者】
：
Qiong-ni ZHU Hong-mei XIE Dan ZHANG Jie LIU Yuan-fu LU 
【机 构】
：
Department of Pharmacology and Key Lab of Basic Pharmacology of Guizhou, Zunyi Medical College, Zuny
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
pregnancy and lactating rats liver bile acids Cyp7a1 and SHP Ntcp and Bsep 
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Aim: Intrahepatic cholestasis of pregnancy (ICP) is a liver disease which may occur in the third trimester of pregnancy.The etiology and pathogenesis of ICP is thought to be closely related to bile acid metabolism.The objective of this study was to examine the regulation of bile acid metabolism in normal pregnant and lactating rats.
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