【摘 要】
：
目的：利用亲水作用液相色谱-电喷雾离子源质谱联用(HILIC/ESI-MS)对白花蛇舌草药材中的强极性组分进行考察.方法：在电喷雾离子源负离子模式下,采用基于基峰强度的特征色谱图谱中的8个共有峰为考察对象,对不同产地的白花蛇舌草及其伪品水线草中的强极性组分进行主成分分析.结果：8个共有峰的准分子离子或加合分子离子的质荷比分别为:m/z 383.2,m/z 399.2,m/z 389.1,m/z 8
【机 构】
：
河北科技大学河北省分析测试研究中心,河北 石家庄 050018
【出 处】
：
2014第三届环渤海色谱质谱学术报告会
论文部分内容阅读
目的：利用亲水作用液相色谱-电喷雾离子源质谱联用(HILIC/ESI-MS)对白花蛇舌草药材中的强极性组分进行考察.
方法：在电喷雾离子源负离子模式下,采用基于基峰强度的特征色谱图谱中的8个共有峰为考察对象,对不同产地的白花蛇舌草及其伪品水线草中的强极性组分进行主成分分析.
结果：8个共有峰的准分子离子或加合分子离子的质荷比分别为:m/z 383.2,m/z 399.2,m/z 389.1,m/z 850.9,m/z 665.3,m/z827.4,m/z 989.4,m/z 1151.1.通过主成分分析,白花蛇舌草药材中的强极性组分具有明显的地域性,且其与伪品水线草成分差异也十分显著.
结论：HILIC/ESI-MS方法可以提供强极性组分一些基本信息,较单纯利用色谱保留时间为参数的指纹图谱分析更加可靠、准确,为进一步了解白花蛇舌草强极性组分提供依据.
其他文献
Molecular imprinting technology is a promising and facile method to produce molecular imprinted polymers (MIPs) with molecular-specific recognition sites to the target molecules.MIPs possess desired s
Molecular imprinting is a versatile and easy method to build selective recognition sites in a stable polymer matrix, and it is also an effective method for the preparation of selective sorbents.The mo
The objective of this paper is to propose a simple and effective pretreatment method for the enrichment of alkaloids.This pretreatment method was also applied to develop improved methods for the prepa
Glycan profiles on monoclonal antibodies (mAbs) impact the therapeutic efficacy.Glycosylation is affected by many factors such as cell line in which the mAb is produced as well as specific production
In this study, on-line concentration-capillary electrophoresis was used to determine catecholamines.Different methods were employed namely, CE-UV and CE-LIF combined with cation-selective exhaustive i
Using hydrophilic PVDF membranes as the supporting membrane and recopamine as the model molecule, the recopomine molecular imprinted polymer membranes (MIM) were synthesized by the thermal polymerizat
β-blockers, like atenolol, esmolol, and bisoprolol, are a group of therapeutically important drugs widely used in the treatment of angina, cardiac arrhythmias, hypertension, and so on.However, an over
Benzo[a]pyrene (BaP) is the most dangerous chemical amongl6 PAHs considered as priority pollutants by the US EPA, and it is frequently sought as an indicator of PAHs contamination.Owing to the low wat
Local anaesthetics, procaine (Pro), lidocaine (Lid), ropivacaine (Rop) and bupivacaine (Bup), are often used intravenously, epidurally, topically or subcutaneously to relieve pain during and after med
建立了测定禽肉中盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物残留量的液相色谱-串联质谱法.鸡肉(鸭肉)样品用氢氧化钠溶液水解,盐酸调节PH值,以乙腈作为提取溶剂,经固相萃取柱净化,洗脱液经氮气吹干后定容,液相色谱-串联质谱法分析盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物残留量.结果表明,添加浓度为0.01-0.05mg/kg,禽肉中盐酸金刚烷胺、盐酸金刚乙胺、地塞