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  5. Depleted Aldehyde Dehydrogenase1A1 Reverses Cisplatin Resistance of Non-small Cell Lung Cancer Cells

Depleted Aldehyde Dehydrogenase1A1 Reverses Cisplatin Resistance of Non-small Cell Lung Cancer Cells

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：wwwww1980wwwww
【摘 要】
：
OBJECTIVE: Cisplatin is the first-line chemotherapy for the treatment of non-small cell lung cancer (NSCLC).However, its resistance has been a major obstacle in the management of NSCLC.Aldehyde dehydr
【作 者】
：
Y.Y.Wei S.S.Wu W.Xu Y.Liang J.Q.Wu 
【机 构】
：
Department of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Chin
【出 处】
：
2015中国老年医学和老年健康产业大会
【发表日期】
：
2015年7期
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OBJECTIVE: Cisplatin is the first-line chemotherapy for the treatment of non-small cell lung cancer (NSCLC).However, its resistance has been a major obstacle in the management of NSCLC.Aldehyde dehydrogenaselA1 (ALDH1A1) over-expression has been observed in a variety of cancers, including lung cancer.The purpose of this study was to investigate the effect of ALDH1A1 expression on cisplatin resistance and to explore potential mechanism.
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