Different pathogenesis between rapid and conventional progressors in SIVmac239-infected rhesus macaq

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户:liongliong426
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  Infection of Indian-origin rhesus macaques(RM)with simian immunodeficiency virus(SIV)or simian-HIV(SHIV)provided useful tools for HIV/AIDS research.Given AIDS is a disease that affects human of diverse origins,itis of importance to examine animals with different geographical background.To examine the risk factors that may influence the rate of disease progression in SIVmac239-infected rhesus macaques of Chinese-origin.12 Chinese RMs were infected with 1000~1500 TCID50(n=5)and 10000TCID50(n=7)of S1Vmac239 virus,respectively.
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