Molecular Imaging of disease-related pathology in neurodegenerative disorders

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：xiazaiyigeshishi

【摘要】

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【作者】

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Kazuhiko YANAI Nobuyuki OKAMURA Victor L VILLEMAGNE

【机构】

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Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai 980-8575,Japan

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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PET amyloid Aβ α-synuclein tau protein molecular imaging

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Aim: Alzheimers disease (AD) and other neurodegenerative dementia belong to a family of protein mis-folding diseases.These diseases are characterized by the accumulation of insoluble protein aggregates containing an enriched β-sheet structure.AD is pathologically characterized by the extensive deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles.

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Molecular Imaging of disease-related pathology in neurodegenerative disorders

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