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  5. Myricitrin protects against methylglyoxal-induced mitochondrial dysfunction in SHSY5Y cells via trap

Myricitrin protects against methylglyoxal-induced mitochondrial dysfunction in SHSY5Y cells via trap

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：kisswc69
【摘 要】
：
Aim: Methylglyoxal (MGO), a dicarbonyl metabolite, is a major precursor of advanced glycation end products (AGEs).Myricitrin is a flavanoid isolated from the root bark of Myrica cerifera.The present s
【作 者】
：
Yue-hua WANG Yang LU Hai-tao YU Yi ZHANG Lian-hua FANG Shou-bao WANG Guo-rong HE Xiao-ping PU Guan-hua DU 
【机 构】
：
Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking Univers
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
myricitrin methylglyoxal advanced glycation end products (AGEs) mitochondria SH- 
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Aim: Methylglyoxal (MGO), a dicarbonyl metabolite, is a major precursor of advanced glycation end products (AGEs).Myricitrin is a flavanoid isolated from the root bark of Myrica cerifera.The present study was to evaluate the effect of myricitrin against MGO-induced cytotoxicity in SH-SY5Y cells and further investigate the mechanism.
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