Lysine Monomethylation is Critical for IRF4-Mediated Transcriptional Regulation of Th2 Lineage Commi

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：lllwan1

【摘要】

：

【作者】

：

Jia Nie Fuxiang Zhu Zhaoyuan Hui Zhao Shan Thomas Montavon Andy Tsun Zhengfan Jiang lie Wang Thomas Jenuwein Bin Li

【机构】

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Key Laboratory of Molecular Virology & Immunology,Unit of Molecular Immunology,Institut Pasteur of S

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

Th2 IRF4 SUV39HI Methylation

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　　Interferon regulatory factor 4 (IRF4) regulates the transcription of genes essential for the differentiation and function of multiple Th/Treg subsets, including Th2, Th9, Thl7 and Treg.However, the molecular mechanisms underlying IRF4-mediated transcriptional regulation in these different T cell subsets remain unclear.

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Lysine Monomethylation is Critical for IRF4-Mediated Transcriptional Regulation of Th2 Lineage Commi

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