Cyanomethylation and Cyclization of Aryl Alkynoates with Acetonitrile under Transition Metal-free Co

来源 :中国化学会第十三届全国有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户:gyk0088
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Cyano group exists in a number of natural products and pharmaceuticals.It is also an important structural motif in organic synthesis because this group can be easily converted into other functional groups such as carboxylic acids,esters,amides,amines,aldehydes,tetrazoles and ketones.1 Except toxic potassium cyanide or sodium cyanide,several compounds such as N-cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS),TMSCN,N-cyanosuccinimide,etc were employed as the cyano sources.
其他文献
  Pyrrole,as an important heterocycle,broadly exists in agrochemicals,natural products,synthetic intermediates and functional materials,ranging from compounds
  Nitrones are not only widely recognized as important building blocks in the synthesis of various natural and biologically active compounds,but also used as
  1989年,Jordan等人[1a]将阳离子型双茂基锆配合物成功地应用于催化吡啶邻位C(sp2)-H与烯烃的加成反应中,但是,该反应必须在有H2存在的条件下才能循环,在随后的几十年研究
  Enantioselective phosphine organocatalysis has advanced rapidly over the past decades as a powerful tool for the preparation of numerous structurally divers
  C-N bond formation reaction plays an important role in organic synthesis,which is often used in the synthesis of natural and synthetic bioactive compounds[1
  N-aryl heterocycles have attracted increasing attention due to their wide applicability in biochemical,biological,medicinal and material sciences.1 The most
  多环芳烃(又称纳米石墨烯或分子石墨烯)在有机光电材料领域具有潜在的重要用途,近年来其设计合成引人注目[1]。合成多环芳烃的一种重要策略是先构造出准平面多环芳烃碳架
  In order to improve bioactivity ofdaidzein,we designed and synthesized a serial ofdaidzein naphthalene sulfonic acid ester derivatives using principles of k
  Despite the fact that the direct C-H transformation of various compounds has been established,tertiary anilines remain a big challenge for transition-metal
  直接选择性的C (sp3)-H官能团化以及碳碳键的形成是有机合成中的重要方法之一。由于C(sp3)-H的活性低并且缺少金属催化的配位点,直接选择性的C (sp3)-H官能团化已经成为