【摘 要】
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Trachealess (Trh), a member of bHLH-PAS transcription factor family, is the master regulator of formation of Drosophila respiratory system.Other proteins regulating Drosophila tracheogenesis downstrea
【机 构】
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Institute of Zoology, Chinese Academy of Sciences, Beijing 100101
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Trachealess (Trh), a member of bHLH-PAS transcription factor family, is the master regulator of formation of Drosophila respiratory system.Other proteins regulating Drosophila tracheogenesis downstream from Trh include Breathless (FGFR), Branchless (FGF), Sprouty and Notch.Many genes regulating Drosophila tracheogenesis have been demonstrated to have their functional homologs in the mammalian lung development, but the mammalian homolog of trh has not been previously reported.
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