The protection effect of a novel Rho-kinase inhibitor, DL0805-2, on pulmonary injured by acute hyper

来源 :The 6th China-Russia International Conference on Medicine(第六 | 被引量 : 0次 | 上传用户：spyxin

【摘要】

：

Aim: DL0805-2 is a novel Rho-kinase inhibitor discovered by high throughput screening during our previous work and it is found to have potent thoracic aorta relaxation effect.In the present study, we

【作者】

：

Tian-yi Yuan Yu-cai Chen Shu Ning Xiao-na Xu Lian-hua Fang Guan-hua Du

【机构】

：

Beijing Key Laboratory of Drug Targets Identification and Drug Screening,Institute of Materia Medica

【出处】

：

The 6th China-Russia International Conference on Medicine(第六

【发表日期】

：

2014年3期

【关键词】

：

DL0805-2 hypertension pulmonary protection

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Aim: DL0805-2 is a novel Rho-kinase inhibitor discovered by high throughput screening during our previous work and it is found to have potent thoracic aorta relaxation effect.In the present study, we firstly investigated the anti-hypertension effect of DL0805-2 in norepinephrine (NE) induced acute hypertension model and mainly focused on its protection effect on pulmonary injury.

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The protection effect of a novel Rho-kinase inhibitor, DL0805-2, on pulmonary injured by acute hyper

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