【摘 要】
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Aim: To explore the efficacy of total saponins, a compound obtained from seeds of Nigella glandulifera Freyn (TSF) in treating arthritic, pain, and inflammation using experimental models.Methods: Comp
【机 构】
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Department of Pharmacology, Xinjiang Institute of Materia Medica,Urumqi, 830004, China
【出 处】
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The 12th Meeting of the Asia Pacific Federation of Pharmacol
论文部分内容阅读
Aim: To explore the efficacy of total saponins, a compound obtained from seeds of Nigella glandulifera Freyn (TSF) in treating arthritic, pain, and inflammation using experimental models.Methods: Complete Freunds adjuvant (CFA) was used to induce the primal, secondary paw edema model, and collagen-induced arthritis (CIA) was used to induce paw edema model to observe anti-arthritic activities of TSF in rats, the alterations in paw volume were reecorded.In addition, acetic acidinduced writhing and xylene-induced ear edema model were used to evaluatethe analgesic, anti-inflammatory effect in mice.
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