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5. Regulation of neuroinflammation by liver X receptors: differential mechanisms through SHP

Regulation of neuroinflammation by liver X receptors: differential mechanisms through SHP

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：flytraker

【摘 要】

：

We have previously reported that endogenous (oxysterols) as well as synthetic (GW3965, TO0901317) ligands of Liver X Receptor (LXR) efficiently suppressed STAT1 inflammatory signals in IFN-gamma-stimu

【作 者】

：

JH LEE I JOU 

【机 构】

：

Chronic Inflammatory Disease Research Center, Department of Pharmacology, Ajou University Medical Sc

【出 处】

：

The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

：

2013年4期

【关键词】

：

liver X receptor small heterodimer partner STAT1 SUMOylation 

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We have previously reported that endogenous (oxysterols) as well as synthetic (GW3965, TO0901317) ligands of Liver X Receptor (LXR) efficiently suppressed STAT1 inflammatory signals in IFN-gamma-stimulated brain astrocytes.

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