To screen microRNAs(miRNAs)related to early mycosis fungoides(MF),differentially expressed miRNAs between tissue samples from 6 patients with early MF and 6 control patients with eczema or lichen planus were screened with a high throughout miRNA PCR array.The differentially expressed miRNAs were then verified by real-time fluorescentquantitative PCR(RT-qPCR)with tissue samples and Mylacell line.The results showed that three differentially expressed miRNAs were showed in the array,which were hsa-miR-378a-5p、hsa-miR-302c-3p、hsa-miR-107.All of them were statistically significantly up-regulated.RT-qPCRresults of tissue samples werein accordance with miRNA array.