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  5. Age-and sex-related differences of organic anion-transporting polypeptide gene expression in livers

Age-and sex-related differences of organic anion-transporting polypeptide gene expression in livers

来源 :中国工程院2014年医学科学前沿论坛第十四次全国临床药理学学术会议暨第六届国际药物警戒与药物安全学术会议 | 被引量 : 0次 | 上传用户：hyc20008
【摘 要】
：
Organic anion-transporting polypeptides (Oatps) play important roles in transporting endogenous substances and xenobiotics into the liver and are implicated in drug-drug interactions.Many factors coul
【作 者】
：
Wei-Yu Hou Shang-Fu Xu Qiong-Ni Zhu Yuan-Fu Lu Xing-Guo Cheng Jie Liu 
【机 构】
：
Key Lab for Basic Pharmacology of Ministry of Health,Zunyi Medical College,Zunyi,563003
【出 处】
：
中国工程院2014年医学科学前沿论坛第十四次全国临床药理学学术会议暨第六届国际药物警戒与药物安全学术会议
【发表日期】
：
2014年3期
【关键词】
：
Oatps gene expression rat liver development aging sex-difference 
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Organic anion-transporting polypeptides (Oatps) play important roles in transporting endogenous substances and xenobiotics into the liver and are implicated in drug-drug interactions.Many factors could influence their expression and result in alterations in drug disposition, efficacy and toxicity.This study was aimed to examine the development-,aging-, and sex-dependent Oatps expression in livers of rats.
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