【摘 要】
：
目的 探讨3.0T磁共振扩散张量成像(diffusion tensor imaging,DTI)技术各向异性(fraction anisotropy,FA)值与皮层下动脉硬化性脑病(subcortical arteriosclerotic encephalopathy,SAE)患者认知功能障碍之间的相关性.方法 收集经临床及影像学诊断为SAE的患者55例及健康老年志愿者30例,均进行常规MRI及D
【机 构】
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西南医科大学,646000 西南医科大学附属中医医院磁共振室
【出 处】
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中国中西医结合学会医学影像专业委员会第十五次全国学术大会暨上海市中西医结合学会医学影像专业委员会2017年学术年会
论文部分内容阅读
目的 探讨3.0T磁共振扩散张量成像(diffusion tensor imaging,DTI)技术各向异性(fraction anisotropy,FA)值与皮层下动脉硬化性脑病(subcortical arteriosclerotic encephalopathy,SAE)患者认知功能障碍之间的相关性.方法 收集经临床及影像学诊断为SAE的患者55例及健康老年志愿者30例,均进行常规MRI及DTI扫描,并分别于脑室前后角及半卵圆中心病灶区域(正常对照组相应区域)测量FA值.结果 SAE患者各病灶区FA值与正常对照组相部位FA值的差异具有统计学意义(P＜0.05)；不同程度认知功能障碍的SAE患者的相应病变部位FA值差异有统计学意义(P＜0.05)：SAE患者的简易精神量表(Mini-mental State Examination,MMSE)评分与患者侧脑室前后角及半卵圆中心病变区域FA值呈显著正相关(相关系数：r左半=0.623,r右半=0.653,r左后=0.717,r右后=0.745,r左前=0.810,r右前=0.835).结论运用3.0 T磁共振DTI技术,通过对SAE患者特定脑白质病变区域的FA值进行测定,能够在一定程度上的反映SAE患者的神经纤维损害程度,建立起FA值与SAE患者认知功能障碍之间的联系.
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