Benzoxazines are the reaction products of amine, phenol and formaldehyde [1].The flammability characteristics of benzoxazines are very similar to the phenolic resin due to the formation of very similar network created after polymerization.Benzoxazine derivatives also exhibit a wide range of biological activities and were used as bacteriocides, fungicides or antitumor agents [2].The Antimicrobial activity studying of benzoxazines are very interesting from the pharmaceutical points of view.Oxidation reactions played a very important role in establishing structures and chemical properties of benzoxazines.