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5. The central deacetylase Sirtuin1 negatively modulates sympathetic hyperactivity in hypertensive rats

The central deacetylase Sirtuin1 negatively modulates sympathetic hyperactivity in hypertensive rats

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：liu723590

【摘 要】

：

Hypertension is characterized by sympathetic hyperactivity,which is associated with pathophysiological progressing of hypertension.The rostral ventral lateral medulla(RVLM)contains presympathetic neur

【作 者】

：

Zhaotang Wu Jiacen Sun Bing Liu Jikui Li Changzhen Ren Xin Tan Weizhong Wang 

【机 构】

：

Department of Physiology,Second Military Medical University,Shanghai 200433,China

【出 处】

：

2016年国际生理学学术大会

【发表日期】

：

2016年6期

【关键词】

：

hypertension RVLM sirtuin1 sympathetic activity 

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　　Hypertension is characterized by sympathetic hyperactivity,which is associated with pathophysiological progressing of hypertension.The rostral ventral lateral medulla(RVLM)contains presympathetic neurons,whose hyperactivity directly results in the elevated blood pressure and sympathetic outflow.

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