An Integrated Quantitative Proteomics Approach for Systemsbiologyof Protein Post-translational Modif

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：aaboo

【摘要】

：

【作者】

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Zhongyi Cheng

【机构】

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Tongji University

【出处】

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中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

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2014年3期

【关键词】

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Protein post-translational modification quantitative proteomics acetylomeb iomar

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The pathway of protein post-translational modification (PTM) play a crucial role in variouspathophysiological conditions, indicating the promising target for personalized medicine.The substrates of PTM regulative enzymes and their specific inhibitors including HDAC,HMT, kinase and E3 ligase are well demonstrated as effective anti-cancer drugs, while howto comprehensively screen the biomarker and targets of those enzymes and correspondinginhibitors remains great challenges.

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An Integrated Quantitative Proteomics Approach for Systemsbiologyof Protein Post-translational Modif

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