The involvement of several enzymes in methanol detoxification in Drosophila melanogaster adults

来源 :The 10th Conference of Insect Physiology, Biochemistry and M | 被引量 : 0次 | 上传用户:yinxiaomei
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Methanol is among the most common short-chain alcohols in fermenting fruits, the natural food and oviposition sites of the fruitfly D.melanogaster.Our previous results showed that cytochrome P450 monooxygenases (CYPs) were associated with methanol detoxification in the larvae.Piperonyl butoxide (PBO), 3-amino-1,2,4-triazole (3-AT), 4-methylpyrazole (4-MP), triphenyl phosphate (TPP) and diethylmeleate (DEM) are the specific inhibitor of CYPs, catalases, alcohol dehydrogenases (ADHs), esterases (ESTs) and glutathione S-transferases (GSTs) respectively.
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