Chirality is one of the most important fundamental features in nature.Most biological molecules are chiral,and many important biological processes involve specific interactions between chiral substances,which dominate the diffusion as well as distribution of biological molecules across natural membranes.In the past several years,our group has been focused on the development of chromogenic chiral fluorescent molecules for enantioselective recognition of bioactive enantiomers,CPL materials and alive cell imaging.The novel chiral fluorescence molecules include: 1.Fluorescence chemosensors based on chiral conjugated polymer[1];2.Tunable fluorescence materials based on RE(Ⅲl)-containing chiral polymer complexes;3.CPL materials based on AIE-active chiral supramolecular assembly,and so on[2].