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  5. REDV-linked biodegradable polymeric micelles as the transfer vector of ZNF580 for the proliferation

REDV-linked biodegradable polymeric micelles as the transfer vector of ZNF580 for the proliferation

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：zhangyili164958807
【摘 要】
：
Recently,a substantial number of studies focused on gene therapy and nonviral gene delivery vectors [1,2].The REDV sequence is one of the main recognition sites for integrin a4βl binding,which leads t
【作 者】
：
Xuefang Hao Juan Lv Qian Li Jiaxu Fan Yakai Feng Marc Behl Andreas Lendlein 
【机 构】
：
School of Chemical Engineering and Technology,Collaborative Innovation Center of Chemical Science an
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
gene delivery block copolymer biodegradable micelle 
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　　Recently,a substantial number of studies focused on gene therapy and nonviral gene delivery vectors [1,2].The REDV sequence is one of the main recognition sites for integrin a4βl binding,which leads to specific interaction between fibronectin and endothelial cells.Herein,a REDV-linked triblock copolymer poly(ethylene glycol)-b-poly(lactide-co-glycolide)-b-poly(ethylene imine) was synthesized via an amidation reaction.
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